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ganoderic acid T

down-regulates expression of both MMP-2 and MMP-9; isolated from Ganoderma lucidum; structure in first source

Also Known As:

GA-T acid cpd

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Zhong, Jian-Jiang: 4 articles (04/2012 - 12/2006)
2.	Chen, Nian-Hong: 2 articles (06/2011 - 01/2010)
3.	Liu, Jian-Wen: 2 articles (01/2010 - 12/2006)
4.	Li, Ying-Bo: 1 article (04/2012)
5.	Liu, Ru-Ming: 1 article (04/2012)
6.	Tang, Wen: 1 article (12/2006)
7.	Wei, Dong-Zhi: 1 article (12/2006)
8.	Zhao, Wei-Ming: 1 article (12/2006)

Related Diseases

1.	Neoplasms (Cancer) 04/15/2012 - "In the current work, ganoderic acid T was modified to produce more effective small-molecule inhibitors of cancer cell proliferation. " 04/15/2012 - "Ganoderic acid T, a triterpenic acid produced by Ganoderma lucidum, has demonstrated therapeutic potential for tumor disease. " 01/01/2010 - "Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression." 06/15/2011 - "The function of p53 induced by ganoderic acids (GAs) in anti-invasion was unknown, although our previous work reported the inhibition of tumor invasion and metastasis by Ganoderic acid T (GA-T). "
2.	Virus Diseases (Viral Diseases) 04/30/2023 - "Ganoderic acid T (GA-T) is an important triterpene of Ganoderma lucidum, which is utilized to treat viral infections. "
3.	Neoplasm Metastasis (Metastasis) 06/15/2011 - "The function of p53 induced by ganoderic acids (GAs) in anti-invasion was unknown, although our previous work reported the inhibition of tumor invasion and metastasis by Ganoderic acid T (GA-T). "
4.	Lung Neoplasms (Lung Cancer) 12/23/2006 - "Ganoderic acid T from Ganoderma lucidum mycelia induces mitochondria mediated apoptosis in lung cancer cells."
5.	Infections 04/30/2023 - "Transcriptome profiling and bioinformatic analysis of the effect of ganoderic acid T prevents Sendai virus infection."

Related Drugs and Biologics

1.	Acids
2.	Matrix Metalloproteinases (MMPs)
3.	Triterpenes