2- chloro- N- (4- chlorobiphenyl- 2- yl)nicotinamide

an industrial fungicide

Also Known As:

boscalid

Networked: 19 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Biphenyl Compounds: 7
        2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide: 19
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Nicotinic Acids: 13
      - Niacinamide: 2223
        2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide: 19
- Heterocyclic Acids
  - Nicotinic Acids: 13
    - Niacinamide: 2223
      - 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide: 19

Experts

1.	Jiang, Jiazhen: 2 articles (01/2021 - 11/2020)
2.	Qi, Suzhen: 2 articles (01/2021 - 11/2020)
3.	Qian, Le: 2 articles (01/2021 - 11/2020)
4.	Schlenk, Daniel: 2 articles (01/2021 - 11/2020)
5.	Wang, Chengju: 2 articles (01/2021 - 11/2020)
6.	Fernández-Ortuño, Dolores: 2 articles (11/2016 - 04/2015)
7.	Brusa, Davide: 1 article (09/2021)
8.	Gallez, Bernard: 1 article (09/2021)
9.	Isenborghs, Pauline: 1 article (09/2021)
10.	Jordan, Bénédicte F: 1 article (09/2021)

Related Diseases

1.	Infections 06/01/2023 - "Furthermore, IV4 could completely inhibit infection cushion formation of S. sclerotiorum on rape leaves and achieved a preventive efficacy of 90.2 % at 500 μM, which was on the same level as that of commercial boscalid at 30 μM (88.7 %). " 01/01/2020 - "ceranae infection significantly decreased honeybee survival whereas the fungicide boscalid had no effect on uninfected bees. " 04/01/2023 - "Queen exposure to boscalid had detrimental consequences on the colonies they later established regarding brood production, Varroa destructor infection and pollen storage but not nectar storage and population size. " 01/01/2017 - "Thus, the application of boscalid + pyraclostrobin and cyprodinil + fludioxonil mixtures may also be used in large-scale applications to reduce Calonectria diseases because they effectively managed leaf and stem infections. "
2.	Branchiootic syndrome 01/01/2017 - "The linkage map also identified two mutations, located in the previously described genes Bos1 and BcsdhB, that conferred resistance to the fungicides boscalid and iprodione. " 11/01/2016 - "Resistance to boscalid, fenhexamid, iprodione, and pyraclostrobin was found to be caused by amino acid substitutions on target proteins, including H272R/Y in SdhB, F412I/S/V in Erg27, I365 N/S in Bos1, and G143A in Cytb, respectively. " 03/09/2021 - "Resistance conferring mutations were found in a selection of isolates characterized as resistant to thiophanate-methyl, iprodione, pyraclostrobin, fenhexamid, and boscalid including E198A in β-tubulin; I365N/S, Q369P, and N373S in bos1; G143A in cytb; P238S, N369D, and F412I/S in erg27; and P225F and H272R/Y in sdhB, respectively. " 04/01/2015 - "Resistance to thiophanate-methyl, iprodione, boscalid, pyraclostrobin, and fenhexamid was based on target gene mutations that conferred E198A and F200Y in β-tubulin, I365N/S in Bos1, H272R/Y in SdhB, G143A in Cytb, and T63I and F412S in Erg27. "
3.	Mitochondrial Diseases (Mitochondrial Disease) 09/26/2021 - "In conclusion, short-term exposure to Boscalid and Bixafen induces a mitochondrial dysfunction in human cells." 09/26/2021 - "The Short-Term Exposure to SDHI Fungicides Boscalid and Bixafen Induces a Mitochondrial Dysfunction in Selective Human Cell Lines." 10/10/2023 - "We selected low concentrations of boscalid (0.5 µM) and pyraclostrobin (0.25 µM) that did not induce a mitochondrial dysfunction in liver cells when used separately. "
4.	Hypersensitivity (Allergy) 12/01/2014 - "Substitutions at position H272 responsible for a high level of resistance to boscalid conferred sensitivity (H272R), hypersensitivity (H272Y) or moderate resistance (H272V) to fluopyram. " 01/01/2018 - "alternata Moreover, deletion of Trr1 results in hypersensitivity to the fungicides chlorothalonil and boscalid, and Glr1 deletion mutants are highly sensitive to mancozeb, which is the fungicide mostly used in citrus fields. "
5.	Hypopigmentation (Hypomelanosis) 01/01/2020 - "Developmental defects, including head deformity, hypopigmentation, decreased number of newborn neurons, structural defects around the ventricle, enlarged intercellular space in the brain, and nuclear concentration, were observed in zebrafish embryos after boscalid exposure at 48 hpf. "

Related Drugs and Biologics

1.	pyrachlostrobin (F 500)
2.	iprodione
3.	N- (2,3- dichloro- 4- hydroxyphenyl)- 1- methylcyclohexanecarboxamide
4.	tetrachloroisophthalonitrile (Bravo)
5.	Plant Nectar
6.	Tubulin
7.	Thiophanate (Thiophanate Methyl)
8.	Phytochemicals
9.	Xenobiotics
10.	Proteins (Proteins, Gene)