dimethylaminoethanol pyroglutamate

resulting from the reaction between dimethylaminoethanol and pyroglutamic acid; procholinergic and antipsychotic

Also Known As:

DMAE p-Glu; V0191

Networked: 2 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Amino Alcohols: 20
    - Ethanolamines: 16
      - Deanol: 85
        dimethylaminoethanol pyroglutamate: 2
- Alcohols: 595
  - Amino Alcohols: 20
    - Ethanolamines: 16
      - Deanol: 85
        dimethylaminoethanol pyroglutamate: 2
Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Acidic Amino Acids: 44
    - Glutamates: 45
      - dimethylaminoethanol pyroglutamate: 2
  - Dicarboxylic Amino Acids: 20
    - Glutamates: 45
      - dimethylaminoethanol pyroglutamate: 2

Experts

1.	Zaim, Mohammed: 2 articles (01/2012 - 12/2009)
2.	Dubois, Bruno: 1 article (01/2012)
3.	Kanony-Truc, Claire: 1 article (01/2012)
4.	Murphy, Michael F: 1 article (01/2012)
5.	Pujadas-Navinés, Francesc: 1 article (01/2012)
6.	Rainer, Michael: 1 article (01/2012)
7.	Riordan, Henry J: 1 article (01/2012)
8.	Robert, Philippe: 1 article (01/2012)
9.	Soininen, Hilkka: 1 article (01/2012)
10.	Touchon, Jacques: 1 article (01/2012)

Related Diseases

1.	Cognitive Dysfunction 12/01/2009 - "The present study undertook preclinical and clinical evaluations to test a potential therapeutic utility for DMAE p-Glu in cognitive impairments related to central cholinergic deficit. " 12/01/2009 - "These results indicate that DMAE p-Glu reduces the deleterious effect of scopolamine on long-term memory in healthy volunteers and suggest that DMAE p-Glu might be effective in reducing memory deficits in patients with cognitive impairment."
2.	Memory Disorders (Memory Loss) 12/01/2009 - "Clinical study results show that scopolamine induced a memory deficit and that DMAE p-Glu produced a significant positive effect on scores in the Buschke test, as well as a slight but significant difference on choice reaction time. " 12/01/2009 - "These results indicate that DMAE p-Glu reduces the deleterious effect of scopolamine on long-term memory in healthy volunteers and suggest that DMAE p-Glu might be effective in reducing memory deficits in patients with cognitive impairment." 12/01/2009 - "In rat experiments, DMAE p-Glu increased the extracellular levels of choline and acetylcholine in the medial prefrontal cortex, as assessed by intracerebral microdialysis, improved performance in a test of spatial memory, and reduced scopolamine-induced memory deficit in passive avoidance behavior. " 12/01/2009 - "Effects of dimethylaminoethanol pyroglutamate (DMAE p-Glu) against memory deficits induced by scopolamine: evidence from preclinical and clinical studies."
3.	Alzheimer Disease (Alzheimer's Disease) 01/01/2012 - "Effect of six months of treatment with V0191 in patients with suspected prodromal Alzheimer's disease."

Related Drugs and Biologics

1.	Scopolamine (Hyoscine)
2.	Choline (Choline Chloride)
3.	Acetylcholine (Acetylcholine Chloride)
4.	dimethylaminoethanol pyroglutamate
5.	Cholinergic Agents (Cholinergics)