norgalanthamine

a component of Crinum asiaticum; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Inflammation (Inflammations) 01/01/2023 - "Norgalanthamine also ameliorated inflammation by down-regulating the expression of the pro-inflammatory mediators, TNF-α, IL-1β, and MCP-1, and up-regulating the Nrf2/HO-1 pathway. "
2.	Fibrosis (Cirrhosis) 01/01/2023 - "Collectively, these findings imply that norgalanthamine mitigates CCl4-induced hepatic injury by increasing anti-oxidative activity, down-regulating pro-inflammatory mediators and fibrosis-related genes in the liver.HighlightsNorgalanthamine ameliorated the hepatotoxicity after CCl4 injury.Norgalanthamine" 01/01/2023 - "In addition, norgalanthamine decreased collagen deposition in liver tissue as shown on picrosirius red staining by down-regulating expression of the fibrosis-related genes αSMA and fibronectin. "