Hypermanganesemia with Dystonia Polycythemia and Cirrhosis

Also Known As:

Dystonia-Parkinsonism, Hypermanganesemia, Polycythemia, and Chronic Liver Disease; Hepatic Cirrhosis, Dystonia, Polycythaemia, and Hypermanganesaemia; Hepatic Cirrhosis, Dystonia, Polycythemia, and Hypermanganesemia; Hmdpc; Hypermanganesemia With Dystonia, Polycythemia, And Cirrhosis; Parkinsonism and Dystonia with Hypermanganesemia, Polycythemia, and Chronic Liver Disease

Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Nutritional and Metabolic Diseases: 15
- Metabolic Diseases: 10142
  - Hypermanganesemia with Dystonia Polycythemia and Cirrhosis: 7

Related Diseases

1.	Hypermanganesemia with Dystonia Polycythemia and Cirrhosis
2.	Polycythemia (Erythrocytosis)
3.	Fibrosis (Cirrhosis)
4.	Dystonia (Limb Dystonia)

Experts

1.	Clayton, Peter T: 3 articles (01/2016 - 03/2012)
2.	Mills, Philippa B: 3 articles (01/2016 - 03/2012)
3.	Tuschl, Karin: 3 articles (01/2016 - 03/2012)
4.	Aulakh, Roosy: 2 articles (01/2016 - 03/2012)
5.	Barsottini, Orlando G: 2 articles (01/2016 - 03/2012)
6.	Del Rosario, Maria Luz: 2 articles (01/2016 - 03/2012)
7.	Dyack, Sarah: 2 articles (01/2016 - 03/2012)
8.	Gordon, Kevin: 2 articles (01/2016 - 03/2012)
9.	Gospe, Sidney M: 2 articles (01/2016 - 03/2012)
10.	Gulab, Shamshad: 2 articles (01/2016 - 03/2012)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hypermanganesemia with Dystonia Polycythemia and Cirrhosis:

1.	ManganeseIBA 01/01/2016 - "Syndrome of Hepatic Cirrhosis, Dystonia, Polycythemia, and Hypermanganesemia Caused by Mutations in SLC30A10, a Manganese Transporter in Man." 09/01/2012 - "Mutations in the SLC30A10 gene, encoding a manganese transporter, cause a syndrome of hepatic cirrhosis, dystonia, polycythemia, and hypermanganesemia. " 03/09/2012 - "Syndrome of hepatic cirrhosis, dystonia, polycythemia, and hypermanganesemia caused by mutations in SLC30A10, a manganese transporter in man." 07/01/2017 - "Recent studies found that mutations in the human SLC30A10 gene, which encodes a manganese (Mn) efflux transporter, are associated with hypermanganesemia with dystonia, polycythemia, and cirrhosis (HMDPC). " 10/01/2022 - "Hypermanganesaemia with dystonia, polycythemia, and cirrhosis (HMDPC) is a rare genetic and autosomal recessive disorder that occurs due to mutation of the SLC3A10 gene, which encodes the manganese (Mn) transporter in the body; as a result, Mn accumulates in the brain, liver and muscles. "
2.	Penicillamine (Cuprimine)FDA Link 01/01/2021 - "Penicillamine for Hypermanganesemia With Dystonia, Polycythemia, and Cirrhosis in 2 Sisters."
3.	MetalsIBA 01/01/2019 - "The syndrome of hepatic cirrhosis, dystonia, polycythemia, and hypermanganesemia caused by SLC30A10 mutation is a treatable inherited metal deposition syndrome. "