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human MIRN214 microRNA

RefSeq NR_029627

Also Known As:

MIRN214 microRNA, human; hsa-mir-214; miR-214, human; microRNA-214, human

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleic Acids: 11752
  - RNA: 69704
    - Untranslated RNA: 2850
      - Small Untranslated RNA: 566
        MicroRNAs: 67298
        human MIRN214 microRNA: 6
    - Antisense RNA: 1599
      - MicroRNAs: 67298
        human MIRN214 microRNA: 6
- Antisense Elements (Genetics): 31
  - Antisense RNA: 1599
    - MicroRNAs: 67298
      - human MIRN214 microRNA: 6

Experts

1.	Abd El-Aziz, Nashwa: 1 article (01/2020)
2.	Al-Rikabi, Ammar: 1 article (01/2020)
3.	Alajez, Nehad M: 1 article (01/2020)
4.	Aldahmash, Abdullah: 1 article (01/2020)
5.	Alfayez, Musaad: 1 article (01/2020)
6.	Ali, Arwa M: 1 article (01/2020)
7.	Alsaleh, Khalid A: 1 article (01/2020)
8.	Altheyab, Abdulrhaman: 1 article (01/2020)
9.	Elango, Ramesh: 1 article (01/2020)
10.	Manikandan, Muthurangan: 1 article (01/2020)

Related Diseases

1.	Alagille Syndrome (Alagille-Watson Syndrome) 03/01/2012 - "These observations imply that disease causing mutations in JAG1 linked to the SNP rs8708G will be poorly targeted by hsa-miR-214 when present against a normal allele of JAG1 with rs8708A and will show penetrance of JAG1 mutations as Alagille syndrome, while mutant JAG1 linked to rs8708A against rs8708G on the normal allele will show either no disease or much attenuated symptoms and hence exhibit incomplete penetrance."
2.	Stomach Neoplasms (Stomach Cancer) 01/01/2015 - "In addition, rs114673809 modified the binding of hsa-miR-214 to MTHFR as well as MTHFR protein levels in gastric cancer patients. "
3.	Neoplasms (Cancer) 01/01/2023 - "As hsa-mir-214 and hsa-mir-370 are not just involved in melanoma tumor progression, but they can also target endoglin-expressing endothelial cells in the tumor vasculature, these results suggest a complex and differential regulatory mechanism involving the intracellular and extracellular signaling of hsa-mir-214 and hsa-mir-370 in melanoma development and progression."
4.	Melanoma (Melanoma, Malignant) 01/01/2023 - "We show that compared with control cells, overexpression of endoglin in the WM-164 melanoma cell line induces; (i) a significant increase of hsa-mir-214 levels in small extracellular vesicles (EVs) as well as an increased trend in cells; and (ii) significantly lower levels of hsa-mir-370 in the EVs fractions, whereas no significant differences were found in cells. " 01/01/2023 - "Correlation Between Endoglin and Malignant Phenotype in Human Melanoma Cells: Analysis of hsa-mir-214 and hsa-mir-370 in Cells and Their Extracellular Vesicles." 01/01/2023 - "As hsa-mir-214 and hsa-mir-370 are not just involved in melanoma tumor progression, but they can also target endoglin-expressing endothelial cells in the tumor vasculature, these results suggest a complex and differential regulatory mechanism involving the intracellular and extracellular signaling of hsa-mir-214 and hsa-mir-370 in melanoma development and progression."
5.	Breast Neoplasms (Breast Cancer) 01/01/2020 - "Interestingly, interrogation of the expression levels of hsa-miR-205 and hsa-miR-214 in the METABRIC breast cancer dataset revealed significantly poor overall survival in patients with downregulated expression of miR-205 [HR = 0.75 (0.61-0.91)], p = 0.003 and hsa-miR-214 [HR = 0.74 (0.59-0.93) p = 0.008]. "

Related Drugs and Biologics

1.	MicroRNAs (MicroRNA)
2.	Proteins (Proteins, Gene)
3.	Circular RNA
4.	Endoglin
5.	human MIRN452 microRNA