HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

14-O-methyloxymorphone

highly selective and potent mu opioid receptor agonist; structure in first source

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Schmidhammer, Helmut: 3 articles (10/2007 - 02/2005)
2.	Spetea, Mariana: 3 articles (10/2007 - 02/2005)
3.	Al-Khrasani, Mahmoud: 2 articles (10/2007 - 02/2005)
4.	Friedmann, Tamas: 2 articles (10/2007 - 02/2005)
5.	Riba, Pal: 2 articles (10/2007 - 02/2005)
6.	Makuch, Wioletta: 2 articles (03/2007 - 02/2005)
7.	Obara, Ilona: 2 articles (03/2007 - 02/2005)
8.	Przewlocka, Barbara: 2 articles (03/2007 - 02/2005)
9.	Przewlocki, Ryszard: 2 articles (03/2007 - 02/2005)
10.	Schütz, Johannes: 2 articles (03/2007 - 02/2005)

Related Diseases

1.	Neuralgia (Stump Neuralgia) 03/08/2007 - "Local peripheral antinociceptive effects of 14-O-methyloxymorphone derivatives in inflammatory and neuropathic pain in the rat." 03/08/2007 - "In the present study, peripheral components of antinociceptive actions of 6-amino acid-substituted derivatives of 14-O-methyloxymorphone were investigated after local intraplantar (i.pl.) administration in rat models of inflammatory and neuropathic pain. " 03/08/2007 - "The present data indicate that the peripherally restricted 6-amino acid conjugates of 14-O-methyloxymorphone elicit antinociception after local administration, being more potent in inflammatory than in neuropathic pain. "
2.	Visceral Pain 10/19/2007 - "Here, the antinociceptive effects of MOR agonists, the 6beta-glycine derivative of 14-O-methyloxymorphone (HS-731), DAMGO and morphine were evaluated in a mouse model of visceral pain. " 10/19/2007 - "DAMGO and 6beta-glycine substituted 14-O-methyloxymorphone but not morphine show peripheral, preemptive antinociception after systemic administration in a mouse visceral pain model and high intrinsic efficacy in the isolated rat vas deferens."
3.	Pain (Aches) 02/01/2005 - "Peripheral versus central antinociceptive actions of 6-amino acid-substituted derivatives of 14-O-methyloxymorphone in acute and inflammatory pain in the rat."

Related Drugs and Biologics

1.	Acids
2.	Ala(2)-MePhe(4)-Gly(5)- Enkephalin (DAGO)
3.	Morphine (MS Contin)