rat CLIC1 protein

01/01/2023 - "Chloride intracellular channel 1 (CLIC1) has emerged as a therapeutic target in various cancers. "
01/01/2022 - "Multiple reports have demonstrated that highly expressed chloride intracellular channel 1 (CLIC1) exists in a range of malignant tumors and is involved in proliferation, invasion, and migration of cancer cells. "
01/01/2019 - "Chloride intracellular channel 1 (CLIC1) is a promising therapeutic target in cancer due to its intrinsic characteristics; it is overexpressed in specific tumor types and its localization changes from cytosolic to surface membrane depending on activities and cell cycle progression. "
02/01/2015 - "Chloride intracellular channel 1 (CLIC1) has been shown to be upregulated in various malignancies but its exact function remains unclear. "
11/01/2013 - "Chloride intracellular channel 1 is overexpression in hepatic tumor and correlates with a poor prognosis."

12/01/2019 - "Our previous study shows that high Chloride intracellular channel 1 (CLIC1) expression can efficiently enhance invasion and migration of gastric cancer (GC) cells in vitro. "
06/28/2012 - "To investigate the effect of chloride intracellular channel 1 (CLIC1) on the cell proliferation, apoptosis, migration and invasion of gastric cancer cells. "
06/28/2012 - "Function of chloride intracellular channel 1 in gastric cancer cells."
05/01/2012 - "PA28β regulates cell invasion of gastric cancer via modulating the expression of chloride intracellular channel 1."
12/01/2015 - "Chloride intracellular channel 1 (CLIC1) has been demonstrated to be overexpressed in gastric cancer, and elevated CLIC1 expression levels are markedly associated with the processes of tumor cell migration and invasion. "

02/06/2023 - "Chloride intracellular channel 1 (CLIC1) is involved in cell migration and metastasis. "
06/01/2015 - "Here, we found that the expression of chloride intracellular channel 1 (CLIC1) is highly correlative with intraperitoneal metastasis. "
09/30/2022 - "Chloride intracellular channel 1 (CLIC1) plays an important role in the process of cell epithelial transport, and is also involved in tumor invasion and metastasis. "
06/01/2012 - "In this investigation, we used the human colon cancer cell lines LOVO and HT29 as model systems to determine the role of the chloride intracellular channel 1 (CLIC1) in the metastasis of colonic cancer. "
08/18/2009 - "In the present study, metastasis-associated proteins were identified by comparative proteomic analysis and the metastasis-related function of the candidate protein, chloride intracellular channel 1 (CLIC1), was further elucidated. "

01/01/2023 - "To investigate the clinical significance of Chloride Intracellular Channel 1 (CLIC1) expression in esophageal squamous cell carcinoma (ESCC) and its functional contribution and molecular mechanisms to the progression of ESCC. "
01/01/2023 - "Chloride intracellular channel 1 promotes esophageal squamous cell carcinoma proliferation via mTOR signalling."
05/01/2018 - "Background: Recent studies have reported important roles for chloride intracellular channel 1 (CLIC1) in various cancers; however, its involvement in esophageal squamous cell carcinoma (ESCC) remains unclear. "
05/01/2018 - "Chloride intracellular channel 1 as a switch among tumor behaviors in human esophageal squamous cell carcinoma."

10/01/2023 - "We previously discovered a signature of genes, including Chloride intracellular channel 1 (Clic1), whose expression was associated with drug-induced weight gain, and in these studies, we assess the effect of Clic1 inhibition on food intake and body weight in mice. "