calotropin

11/01/2023 - "The main objective of this study was to investigate the potential anti-cancer properties of calotropin against HSC-3 oral squamous cancer cells and to elucidate the underlying mechanisms involved in its action. "
01/01/2023 - "The effects of calotropin on cancer have been extensively studied in preclinical pharmacological studies in vitro using cancer cell lines and in vivo in experimental animal models that have targeted antitumor mechanisms and anticancer signaling pathways. "
01/01/2023 - "The results of our analysis demonstrate that calotropin can be a potential chemotherapeutic/chemopreventive adjunctive agent in cancer pharmacotherapeutic management."
01/01/2023 - "In this updated and comprehensive review, we aimed to analyze and discuss the specific mechanisms and molecular targets of calotropin in cancer treatment to open new perspectives for the adjuvant treatment of different types of cancer. "
01/01/2023 - "An updated pharmacological insight into calotropin as a potential therapeutic agent in cancer."

05/26/2021 - "Based on the antiproliferative activity reported for cardenolides, the activity of calotropin and calotoxin was tested against two common cancer cell lines, human triple-negative breast cancer cell line (MDA-MB-231) and human lung adenocarcinoma cell line (A549). "

11/01/2023 - "Calotropin, a cardiac glycoside obtained from the plant Calotropis gigantea, has demonstrated promising potential as an anti-tumorigenesis compound. "

12/01/2009 - "We set out to evaluate the cytotoxic mechanism of calotropin on human chronic myeloid leukemia K562 cells. "

01/01/2019 - "Calotropin activates YAP through downregulation of LATS1 in colorectal cancer cells."