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CG 0006

a histone deacetylase inhibitor; structure in first source

Also Known As:

CG-0006; CG0006

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Hydroxylamines: 16
    - Hydroxamic Acids: 239
      - CG 0006: 2
- Carboxylic Acids: 973
  - Hydroxy Acids: 94
    - Hydroxamic Acids: 239
      - CG 0006: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - CG 0006: 2

Experts

1.	Choi, Jene: 2 articles (11/2011 - 10/2009)
2.	Hwang, Jung Jin: 2 articles (11/2011 - 10/2009)
3.	Hyun, Young-Lan: 2 articles (11/2011 - 10/2009)
4.	Kim, Choung-Soo: 2 articles (11/2011 - 10/2009)
5.	Lee, Je-Hwan: 2 articles (11/2011 - 10/2009)
6.	Ro, Seonggu: 2 articles (11/2011 - 10/2009)
7.	Jang, Se Jin: 1 article (11/2011)
8.	Kim, Hyun Mi: 1 article (11/2011)
9.	Jang, Sejin: 1 article (10/2009)
10.	Kim, Mi Joung: 1 article (10/2009)

Related Diseases

1.	Neoplasms (Cancer) 11/01/2011 - "CG0006 effects on the proliferation of multiple human cancer cell lines were tested using MTT and MTS assays. " 10/01/2009 - "The HDACI CG0006 may be a potent anticancer drug for solid tumors and leukemia." 10/01/2009 - "We synthesized a novel hydroxamate-based HDACI, CG0006, and assessed its antiproliferative effects on the NCI-60 cancer cell panel and cell lines from liver and stomach cancers that are common in Korea. " 11/01/2011 - "We previously reported that CG0006, a novel hydroxamate-based pan-histone deacetylase inhibitor (HDACI), suppresses the growth of human cancer cells. "
2.	Stomach Neoplasms (Stomach Cancer) 10/01/2009 - "Micromolar levels of CG0006 induced cell death in several breast, central nervous system, colon, hematopoietic, lung, melanoma, ovarian, prostatic, renal, and stomach cancer cell lines. " 10/01/2009 - "We synthesized a novel hydroxamate-based HDACI, CG0006, and assessed its antiproliferative effects on the NCI-60 cancer cell panel and cell lines from liver and stomach cancers that are common in Korea. "
3.	Melanoma (Melanoma, Malignant) 10/01/2009 - "Micromolar levels of CG0006 induced cell death in several breast, central nervous system, colon, hematopoietic, lung, melanoma, ovarian, prostatic, renal, and stomach cancer cell lines. "
4.	Leukemia 10/01/2009 - "The HDACI CG0006 may be a potent anticancer drug for solid tumors and leukemia." 10/01/2009 - "We further analyzed cell death mechanisms activated by CG0006 in HCT116 (colon cancer) and K562 (leukemia) cells. "
5.	Colonic Neoplasms (Colon Cancer) 10/01/2009 - "We further analyzed cell death mechanisms activated by CG0006 in HCT116 (colon cancer) and K562 (leukemia) cells. "

Related Drugs and Biologics

1.	Histone Deacetylase Inhibitors
2.	Cell Cycle Proteins
3.	Estrogen Receptors
4.	Histones (Histone)