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3beta,6beta-dihydroxyolean-12-en-28-oic acid

acetylcholinesterase inhibitor from Warszewiczia coccinea (Rubiaceae)

Also Known As:

3beta,6beta-dihydroxy-olean-12-en-28-oic acid; sumaresinolic acid

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - Pentacyclic Triterpenes: 108
        Oleanolic Acid: 547
        3beta,6beta-dihydroxyolean-12-en-28-oic acid: 1
      - Sapogenins: 26
        Oleanolic Acid: 547
        3beta,6beta-dihydroxyolean-12-en-28-oic acid: 1

Experts

1.	Bermejo, Jaime: 1 article (12/2007)
2.	Branco, Isabel: 1 article (12/2007)
3.	Brouard, Ignacio: 1 article (12/2007)
4.	Cabrita, Eurico J: 1 article (12/2007)
5.	Justino, Jorge: 1 article (12/2007)
6.	Lopes, Rui G: 1 article (12/2007)
7.	Noronha, João P: 1 article (12/2007)
8.	Rauter, Amélia P: 1 article (12/2007)
9.	Silva, Filipa V M: 1 article (12/2007)

Related Diseases

1.

Alzheimer Disease (Alzheimer's Disease)

12/01/2007 - "In addition, nepetidin (2), nepeticin (3), lupendiol (4), (1beta,11alpha)-dihydroxy-lup-20(29)-en-3-one (5), ursolic acid (6), sumaresinolic acid (7) and hederagenin (8), were identified in this Salvia sp. To the best of our knowledge, the compounds 2 and 7 are new constituents in Salvia spp. The acetone, ethanol, butanol and water extracts of the plant were screened for the in vitro inhibitory activity of acetylcholinesterase (AChE) and butyrilcholinesterase (BChE), enzymes which play a role in the Alzheimer disease. "

Related Drugs and Biologics

1.	Enzymes
2.	Butanols (Butyl Alcohols)
3.	Ethanol (Ethyl Alcohol)
4.	Acetylcholinesterase
5.	Ursolic Acid
6.	Acetone
7.	hederagenin