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KBF 611
antituberculosis agent; structure in first source
Also Known As:
4-acetamido-3-fluorobenzaldehyde thiosemicarbazone; KBF-611; KBF611
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Sulfur Compounds: 278
Thiosemicarbazones: 649
Thioacetazone: 270
KBF 611: 1
Semicarbazides: 7
Semicarbazones: 67
Thiosemicarbazones: 649
Thioacetazone: 270
KBF 611: 1
Experts
1.
Dadashzadeh, S
: 1 article (03/2010)
2.
Kobarfard, F
: 1 article (03/2010)
3.
Shafaghi, B
: 1 article (03/2010)
4.
Shahab, F M
: 1 article (03/2010)
Related Diseases
1.
Tuberculosis (Tuberculoses)
03/01/2010 - "
According to the calculated parameters, KBF611 showed a more favourable pharmacokinetics profile than TAZ in terms of half-life (0.89 h compared with 0.57 in mice, p < 0.05, and 2.71 compared with 0.98 in rabbits, p < 0.001) and volume of distribution (1.45 l kg(-1) compared with 0.86 l kg(-1) in mice, p < 0.05, and 1.01 l kg(-1) compared with 0.41 l kg(-1) in rabbits, p < 0.001) for tuberculosis therapy.
"
Related Therapies and Procedures
1.
Therapeutics