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2- chloro- 4- (3- hydroxy- 3- methyl- 8- azabicyclo(3.2.1)oct- 8- yl)- 3- methylbenzonitrile

an androgen receptor modulator; structure in first source

Also Known As:

ACP 105; ACP-105; ACP105

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Aza Compounds: 3
  - Azabicyclo Compounds
    - 2-chloro-4-(3-hydroxy-3-methyl-8-azabicyclo(3.2.1)oct-8-yl)-3-methylbenzonitrile: 1
Heterocyclic Compounds: 198
- Bridged-Ring Heterocyclic Compounds
  - Heterocyclic Bridged Bicyclo Compounds
    - Azabicyclo Compounds
      - 2-chloro-4-(3-hydroxy-3-methyl-8-azabicyclo(3.2.1)oct-8-yl)-3-methylbenzonitrile: 1

Experts

1.	K Karatt, Tajudheen: 1 article (02/2021)
2.	Karakka Kal, Abdul Khader: 1 article (02/2021)
3.	M P, Muhammed Ajeebsanu: 1 article (02/2021)
4.	N, Ibrahimwaseem: 1 article (02/2021)
5.	Philip, Moses: 1 article (02/2021)
6.	Subhahar, Michael Benedict: 1 article (02/2021)
7.	Vazhat, Ramees Abdulla: 1 article (02/2021)

Related Diseases

1.

Dehydration (Water Stress)

02/01/2021 - "The study results suggest the following: (1) ACP-105 is prone to oxidation, which gives corresponding monohydroxylated, dihydroxylated, and trihydroxylated metabolites; (2) along with oxidation, there is a possibility of elimination of water molecule (dehydration) from the third position of the tropine moiety, resulting in the dehydrated analogs of corresponding monohydroxylated, dihydroxylated, and trihydroxylated metabolites; (3) from the study on the metabolites using LC-MS/MS, it is clear that the fragmentation pattern is identical and a great number of fragment ions are common in all the metabolites and the parent drug. "

Related Drugs and Biologics

1.	Ions
2.	tropine