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Mequindox

a synthetic quinoxaline 1,4-dioxide derivative which can effectively improve growth and feed efficiency in animals; structure in first source

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinoxalines: 324
      - Mequindox: 6

Experts

1.	Chen, Dongmei: 2 articles (02/2017 - 11/2015)
2.	Huang, Lingli: 2 articles (02/2017 - 11/2015)
3.	Liu, Zhenli: 2 articles (02/2017 - 11/2015)
4.	Pan, Yuanhu: 2 articles (02/2017 - 11/2015)
5.	Yuan, Zonghui: 2 articles (02/2017 - 11/2015)
6.	Huang, Chongyang: 2 articles (09/2012 - 11/2011)
7.	Lei, Hehua: 2 articles (09/2012 - 11/2011)
8.	Tang, Huiru: 2 articles (09/2012 - 11/2011)
9.	Wang, Yulan: 2 articles (09/2012 - 11/2011)
10.	Zhao, Xiu-Ju: 2 articles (09/2012 - 11/2011)

Related Diseases

1.	Body Weight (Weight, Body) 11/04/2011 - "In this study, we delivered a single dose of mequindox to mice with dosage levels of 15, 75, and 350 mg/kg body weight and collected urine samples over a 7 day period, as well as plasma and liver tissues at 7 days postdose. "
2.	Dysentery 12/01/2013 - "The derivatives of QdNOs (carbadox, olaquindox, mequindox, quinocetone, and cyadox) are the potent synthetic antimicrobial agents that are used for improving the feed efficiency and controlling dysentery in food-producing animals. " 01/01/2022 - "antibacterial, antifungal, anticancer, anti-inflammatory, antiviral, and antiprotozoal activity, etc. Some commercially available drug molecules containing quinoxaline moiety are echinomycin (as antibacterial, antineoplastic, and nucleic acid inhibitor), triostins (cyclic desipeptide as an antibacterial agent), dioxidine and mequindox (as antibacterial agents), carbadox (controlling swine dysentery), desoxycarbadox (as swine growth promoter) and panadipion (as hepatoprotective agent), etc. A large number of quinoxaline analogues possessing different biological activities and their synthetic procedures have been patented worldwide."
3.	Liver Diseases (Liver Disease) 09/07/2012 - "Metabolic profiling of urine revealed that metabolic recovery is achieved for rats exposed to a low or moderate dose of mequindox, whereas high levels of mequindox exposure trigger liver dysfunction, causing no such recovery. "
4.	Enteritis 11/11/2015 - "Mequindox (MEQ), a quinoxaline-N,N-dioxide antibacterial agent used to control bacterial enteritis in various food-producing animals, is a potential violative residue in food animal-derived products. "
5.	Bacterial Infections (Bacterial Infection) 02/01/2017 - "Quinocetone (QCT) and mequindox (MEQ) are widely used in China for the prevention of bacterial infections and promoting animal growth, but their abuse causes a potential threat to human health. "

Related Drugs and Biologics

1.	A 7 (A-7)
2.	Quinoxalines
3.	Carbadox
4.	Anti-Bacterial Agents (Antibiotics)
5.	quinocetone
6.	Nucleic Acids
7.	Echinomycin
8.	Antiviral Agents (Antivirals)
9.	Antineoplastic Agents (Antineoplastics)
10.	Anti-Infective Agents (Microbicides)