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2-18F-fluoropropionic acid

a PET imaging agent for prostate cancer; structure in first source

Also Known As:

(18)F-FPA

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Halogenated Hydrocarbons: 42
    - Fluorinated Hydrocarbons: 4
      - Fluorocarbons: 1209
        2-18F-fluoropropionic acid: 2

Experts

1.	Hu, Kongzhen: 1 article (01/2016)
2.	Huang, Tingting: 1 article (01/2016)
3.	Li, Sijin: 1 article (01/2016)
4.	Liang, Xiang: 1 article (01/2016)
5.	Tang, Ganghua: 1 article (01/2016)
6.	Wang, Hongliang: 1 article (01/2016)
7.	Wu, Zhifang: 1 article (01/2016)
8.	Larson, Steven M: 1 article (10/2009)
9.	Pillarsetty, Nagavarakishore: 1 article (10/2009)
10.	Punzalan, Blesida: 1 article (10/2009)

Related Diseases

1.	Neoplasms (Cancer) 01/12/2016 - "PET imaging with (18)F-FDG, (18)F-FAC and (18)F-FPA revealed the high uptake in both tumor and inflammatory lesions. " 10/01/2009 - "The %ID/g values for (18)F-FPA and (14)C-acetate 1 h after tail vein injection were 7.08 +/- 0.80 and 0.36 +/- 0.08 in tumor, and the corresponding tumor-to-muscle ratios were 1.94 and 2.06, respectively. " 10/01/2009 - "Comparative imaging studies demonstrate the superior performance of (18)F-FPA over (18)F-FDG for imaging prostate cancer, with excellent tumor-to-background contrast. " 01/12/2016 - "The ratios of tumor-to-inflammation were 1.63 ± 0.28 for (18)F-FDG, 1.20 ± 0.38 for (18)F-FAC, and 1.41 ± 0.33 for (18)F-FPA at 60 min postinjection, respectively. " 01/12/2016 - "Biodistributions of (18)F-FAC, (18)F-FPA and (18)F-FBA were determined on normal Kunming mice, and positron emission tomography (PET) imaging with these tracers were performed on the separate tumor-bearing mice model and inflammation mice model in comparison with (18)F-FDG. "
2.	Prostatic Neoplasms (Prostate Cancer) 10/01/2009 - "(18)F-FPA has potential for use in the clinical diagnosis of prostate cancer in humans." 10/01/2009 - "2-18F-Fluoropropionic acid as a PET imaging agent for prostate cancer." 10/01/2009 - "Comparative imaging studies demonstrate the superior performance of (18)F-FPA over (18)F-FDG for imaging prostate cancer, with excellent tumor-to-background contrast. " 10/01/2009 - "The data presented here indicate that (18)F-FPA accumulates in prostate cancers with high tumor-to-background ratios. "
3.	Inflammation (Inflammations) 01/12/2016 - "The ratios of tumor-to-inflammation were 1.63 ± 0.28 for (18)F-FDG, 1.20 ± 0.38 for (18)F-FAC, and 1.41 ± 0.33 for (18)F-FPA at 60 min postinjection, respectively. " 01/12/2016 - "Biodistributions of (18)F-FAC, (18)F-FPA and (18)F-FBA were determined on normal Kunming mice, and positron emission tomography (PET) imaging with these tracers were performed on the separate tumor-bearing mice model and inflammation mice model in comparison with (18)F-FDG. "

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