11,15-O-dimethylprostaglandin E2

Also Known As:

11,15-O-dimethyl prostaglandin E2; ONO-AE1-259-01

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - Eicosanoids: 3262
      - Prostaglandins: 17100
        Prostaglandins E: 2673
        Dinoprostone: 10047
        11,15-O-dimethylprostaglandin E2: 3
Biological Factors: 2472
- Inflammation Mediators: 1113
  - Autacoids: 276
    - Eicosanoids: 3262
      - Prostaglandins: 17100
        Prostaglandins E: 2673
        Dinoprostone: 10047
        11,15-O-dimethylprostaglandin E2: 3

Experts

1.	Hessel, Amanda Titzel: 1 article (01/2017)
2.	Marafiga, Joseane Righes: 1 article (01/2017)
3.	Mello, Carlos Fernando: 1 article (01/2017)
4.	Miyazato, Lígia Gomes: 1 article (01/2017)
5.	Oliveira, Mauro Schneider: 1 article (01/2017)
6.	Pillat, Micheli Mainardi: 1 article (01/2017)
7.	Ribeiro, Leandro Rodrigo: 1 article (01/2017)
8.	Santos, Aline Carré: 1 article (01/2017)
9.	Temp, Fernanda Rossatto: 1 article (01/2017)
10.	Ahmad, Muzamil: 1 article (07/2010)

Related Diseases

1.	Ganglion Cysts (Ganglion) 08/15/2009 - "ONO-AE1-259-01 concentration-dependently prevented NMDA-induced cell loss in ganglion cell layer and reduction in thickness of inner plexiform layer. "
2.	Stroke (Strokes) 07/08/2010 - "Here, we investigated the importance of the EP2 receptor in short- and long-term ischemic outcomes by subjecting wildtype (WT) and EP2 knockout (EP2-/-) mice to two distinct and complementary stroke models [transient and permanent middle cerebral artery occlusion (tMCAO and pMCAO)] and by using the EP2 receptor agonist ONO-AE1-259-01. "
3.	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 07/08/2010 - "Here, we investigated the importance of the EP2 receptor in short- and long-term ischemic outcomes by subjecting wildtype (WT) and EP2 knockout (EP2-/-) mice to two distinct and complementary stroke models [transient and permanent middle cerebral artery occlusion (tMCAO and pMCAO)] and by using the EP2 receptor agonist ONO-AE1-259-01. "
4.	Wounds and Injuries (Trauma) 08/15/2009 - "These results indicate that ONO-AE1-259-01 protects the excitotoxic injuries in the rat retina, and that the prostanoid EP(2) receptor may be a target for neuroprotective intervention in the retinal diseases associated with glutamate-induced excitotoxicity, such as glaucoma and diabetic retinopathy."
5.	Status Epilepticus (Complex Partial Status Epilepticus) 01/01/2017 - "The effect of ONO-AE1-259-01 on cell death in the hippocampal formation of adult male mice seven days after pilocarpine-induced status epilepticus (SE) was also evaluated. "

Related Drugs and Biologics

1.	Glutamic Acid (Glutamate)
2.	N-Methylaspartate (NMDA)
3.	Prostaglandins
4.	Pilocarpine (Ocusert)
5.	Pentylenetetrazole (Metrazol)