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NU 3153

an antifolate

Also Known As:

NU-3153; NU3153

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Dipyridamole: 3288
      - NU 3153: 1

Experts

1.	Barlow, Hannah: 1 article (07/2009)
2.	Barton, Marion: 1 article (07/2009)
3.	Curtin, Nicola J: 1 article (07/2009)
4.	Golding, Bernard T: 1 article (07/2009)
5.	Griffin, Roger J: 1 article (07/2009)
6.	Lin, Mei-Ju: 1 article (07/2009)
7.	Newell, David R: 1 article (07/2009)
8.	Northen, Julian S: 1 article (07/2009)
9.	Saravanan, Kappusamy: 1 article (07/2009)
10.	Thomas, Huw D: 1 article (07/2009)

Related Diseases

1.	Neoplasms (Cancer) 07/01/2009 - "Plasma NU3153 concentrations commensurate with rescue inhibition in vitro were maintained for at least 16 hours following administration of NU3166 to mice at 120 mg/kg. However, maximum inhibition of thymidine incorporation into tumors was only 50%, which was insufficient to enhance pemetrexed antitumor activity in vivo. "

Related Drugs and Biologics

1.	Thymidine
2.	Pemetrexed (MTA)