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methylophiopogonanone A

isolated from Ophiopogon japonicus; structure in first source

Networked: 4 relevant articles (1 outcomes, 2 trials/studies)

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Bio-Agent Context: Research Results

Experts

1.	Chang, Shanquan: 1 article (01/2022)
2.	Gong, Puyang: 1 article (01/2022)
3.	Qi, Jin: 1 article (01/2022)
4.	Tian, YuShan: 1 article (01/2022)
5.	Xu, Juntao: 1 article (01/2022)
6.	Yu, BoYang: 1 article (01/2022)
7.	Li, Zhao: 1 article (01/2020)
8.	Wu, Ying-Ying: 1 article (01/2020)
9.	Yu, Bei-Xin: 1 article (01/2020)
10.	Chen, Cai: 1 article (06/2016)

Related Diseases

1.	Brain Ischemia (Cerebral Ischemia) 01/01/2015 - "Methylophiopogonanone A (MO-A), an active homoisoflavonoid of the Chinese herb Ophiopogon japonicus which has been shown to have protective effects on cerebral ischemia/reperfusion (I/R) injury, has been demonstrated to have anti-inflammatory and anti-oxidative properties. " 01/01/2020 - "Methylophiopogonanone A (MO-A), a homoisoflavonoid extracted from Ophiopogon japonicus, has been shown to attenuate myocardial apoptosis and improve cerebral ischemia/reperfusion injury. " 01/01/2015 - "Methylophiopogonanone A Protects against Cerebral Ischemia/Reperfusion Injury and Attenuates Blood-Brain Barrier Disruption In Vitro."
2.	Atherosclerosis 01/30/2022 - "In our study, Ophiopogonis Radix was found to protect against atherosclerosis through suppressing ox-LDL induced macrophage foam cell formation and two potential compounds were identified by biospecific cell extraction including methylophiopogonanone A and methylophiopogonanone B. "
3.	Myocardial Ischemia (Ischemic Heart Diseases) 06/01/2016 - "In this study we investigated the effects of methylophiopogonanone A (MO-A), a major homoisoflavonoid in Ophiopogon japonicus, on myocardial ischemia/reperfusion (I/R) injury. "
4.	Reperfusion Injury 01/01/2020 - "Methylophiopogonanone A (MO-A), a homoisoflavonoid extracted from Ophiopogon japonicus, has been shown to attenuate myocardial apoptosis and improve cerebral ischemia/reperfusion injury. " 01/01/2015 - "Methylophiopogonanone A Protects against Cerebral Ischemia/Reperfusion Injury and Attenuates Blood-Brain Barrier Disruption In Vitro."
5.	Ischemia 06/01/2016 - "Methylophiopogonanone A suppresses ischemia/reperfusion-induced myocardial apoptosis in mice via activating PI3K/Akt/eNOS signaling pathway."

Related Drugs and Biologics

1.	methylophiopogonanone B
2.	oxidized low density lipoprotein