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timosaponin AIII

nootropic agent from Anemarrhena asphodeloides; structure in first source

Also Known As:

timosaponin A3

Networked: 38 relevant articles (2 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - Saponins: 2867
    - timosaponin AIII: 38
Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - timosaponin AIII: 38

Experts

1.	Ding, Yue: 3 articles (01/2021 - 10/2016)
2.	Lu, Lu: 3 articles (01/2021 - 10/2016)
3.	Lee, Sang Yeol: 3 articles (01/2020 - 01/2016)
4.	Song, Shao-Jiang: 3 articles (01/2019 - 01/2017)
5.	Yao, Guo-Dong: 3 articles (01/2019 - 01/2017)
6.	Kim, Dong-Hyun: 3 articles (04/2015 - 08/2009)
7.	Jang, Hyeung-Jin: 2 articles (04/2022 - 03/2019)
8.	Kim, Yumi: 2 articles (04/2022 - 03/2019)
9.	Na, Yun-Cheol: 2 articles (04/2022 - 03/2019)
10.	Hsieh, Yi-Hsien: 2 articles (03/2021 - 01/2019)

Related Diseases

1.	Memory Disorders (Memory Loss) 08/01/2009 - "Timosaponin AIII, a saponin isolated from Anemarrhena asphodeloides, ameliorates learning and memory deficits in mice."
2.	Inflammation (Inflammations) 09/01/2019 - "Protective Effects of Timosaponin AIII against UVB-Radiation Induced Inflammation and DNA Injury in Human Epidermal Keratinocytes."
3.	Neoplasms (Cancer) 12/01/2018 - "This review aims to give a systematic summary of the study of timosaponin AIII to reveal its anti-tumor activities by investigating invasion and migration, apoptosis, autophagy and reversing multi-drug resistance. " 07/19/2023 - "The Potential Role of Timosaponin-AIII in Cancer Prevention and Treatment." 09/15/2020 - "Timosaponin AIII (TAIII), an active component with anti-tumor activity from Anemarrhena asphodeloides Bunge, can induce both autophagy and apoptosis of cancer cells. " 12/01/2018 - "These meaningful findings may provide novel insights on exploiting timosaponin AIII as a new anti-tumor agent." 12/01/2018 - "Timosaponin AIII: A novel potential anti-tumor compound from Anemarrhena asphodeloides."
4.	Triple Negative Breast Neoplasms 01/01/2013 - "The aim of this study was to investigate the mechanisms by which Timosaponin AIII (TAIII) is able to inhibit HGF-induced invasion activity in the triple negative breast cancer cell line MDA-MB-231. "
5.	Precocious Puberty 03/16/2023 - "This study aimed to investigate the effect of timosaponin AIII (TAIII) on the precocious puberty and its possible mechanisms in mice. " 03/16/2023 - "Timosaponin AIII attenuates precocious puberty in mice through downregulating the hypothalamic-pituitary-gonadal axis."

Related Drugs and Biologics

1.	Saponins
2.	Therapeutic Uses
3.	Paclitaxel (Taxol)
4.	p38 Mitogen-Activated Protein Kinases
5.	sarsasapogenin
6.	Actin Depolymerizing Factors (Cofilins)
7.	Catenins
8.	Ginsenosides
9.	Cathepsin C
10.	Caspases

Related Therapies and Procedures

1.	Therapeutics
2.	Chinese Traditional Medicine (Traditional Chinese Medicine)