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3,4- dihydro- N- (3- ((2- hydroxy- 3- methylphenyl)thio)- 2- methylpropyl)- 2H- 1,5- benzoxathiepin- 3- amine

an NaV1.5 channel blocker; structure in first source

Also Known As:

F 15741; F-15741; F15741

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Benzothiepins: 2
    - 3,4-dihydro-N-(3-((2-hydroxy-3-methylphenyl)thio)-2-methylpropyl)-2H-1,5-benzoxathiepin-3-amine: 1
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzothiepins: 2
      - 3,4-dihydro-N-(3-((2-hydroxy-3-methylphenyl)thio)-2-methylpropyl)-2H-1,5-benzoxathiepin-3-amine: 1

Experts

1.	Borras, Maud: 1 article (07/2009)
2.	Colpaert, Francis: 1 article (07/2009)
3.	Cuisiat, Florence: 1 article (07/2009)
4.	Le Grand, Bruno: 1 article (07/2009)
5.	Létienne, Robert: 1 article (07/2009)
6.	Mas, Agnes: 1 article (07/2009)
7.	Pignier, Christophe: 1 article (07/2009)
8.	Rolland, Françoise: 1 article (07/2009)
9.	Vacher, Bernard: 1 article (07/2009)

Related Diseases

1.	Ischemia 07/23/2009 - "The compound, 3,4-dihydro-N-[(2S)-3-[(2-hydroxy-3-methylphenyl)thio]-2-methylpropyl]-2H-(3R)-1,5-benzoxathiepin-3-amine (2d) (F 15741), blocks the late component of the Na(+) currents and greatly reduces veratridine- or ischemia-induced contracture in isolated tissue and whole heart. "
2.	Contracture 07/23/2009 - "The compound, 3,4-dihydro-N-[(2S)-3-[(2-hydroxy-3-methylphenyl)thio]-2-methylpropyl]-2H-(3R)-1,5-benzoxathiepin-3-amine (2d) (F 15741), blocks the late component of the Na(+) currents and greatly reduces veratridine- or ischemia-induced contracture in isolated tissue and whole heart. "

Related Drugs and Biologics

1.	Veratridine
2.	Amines