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Arabidopsis ATXR5 protein

RefSeq NM_121016

Also Known As:

ATXR5 protein, Arabidopsis; ARABIDOPSIS TRITHORAX-RELATED PROTEIN 5

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - One-Carbon Group Transferases
      - Methyltransferases: 5778
        Arabidopsis ATXR5 protein: 3
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Plant Proteins: 334
    - Arabidopsis Proteins: 5
      - Arabidopsis ATXR5 protein: 3

Experts

1.	Cheng, Harrison: 1 article (01/2022)
2.	Do, Truman: 1 article (01/2022)
3.	Ecker, Joseph R: 1 article (01/2022)
4.	Feng, Suhua: 1 article (01/2022)
5.	Jacobsen, Cassidy E: 1 article (01/2022)
6.	Jacobsen, Steven E: 1 article (01/2022)
7.	Khnkoyan, Zhanna: 1 article (01/2022)
8.	Liu, Qikun: 1 article (01/2022)
9.	Naranbaatar, Bilguudei: 1 article (01/2022)
10.	O'Malley, Ronan C: 1 article (01/2022)

Related Diseases

1.

Genomic Instability

01/01/2021 - "In Arabidopsis thaliana, genome stability is maintained during DNA replication by the H3.1K27 methyltransferases ARABIDOPSIS TRITHORAX-RELATED PROTEIN 5 (ATXR5) and ATXR6, which catalyze the deposition of K27me1 on replication-dependent H3.1 variants. "
06/20/2017 - "In plants, the histone H3.1 lysine 27 (H3K27) mono-methyltransferases ARABIDOPSIS TRITHORAX RELATED PROTEIN 5 and 6 (ATXR5/6) regulate heterochromatic DNA replication and genome stability. "
01/01/2022 - "ARABIDOPSIS TRITHORAX-RELATED PROTEIN 5 (ATXR5) AND ATXR6 are required for the deposition of H3K27me1 and for maintaining genomic stability in Arabidopsis Reduction of ATXR5/6 activity results in activation of DNA damage response genes, along with tissue-specific derepression of transposable elements (TEs), chromocenter decompaction, and genomic instability characterized by accumulation of excess DNA from heterochromatin. "

Related Drugs and Biologics

1.	Methyltransferases
2.	Lysine (L-Lysine)
3.	Histones (Histone)
4.	Heterochromatin
5.	DNA Transposable Elements (Element, IS)
6.	DNA (Deoxyribonucleic Acid)
7.	TES