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3-deoxysappanchalcone

Anti-allergic from the roots and heartwood of Caesalpinia sappan; structure in first source

Networked: 6 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Lee, Mee-Hyun: 3 articles (06/2021 - 08/2019)
2.	Shim, Jung-Hyun: 3 articles (06/2021 - 08/2019)
3.	Yoon, Goo: 2 articles (06/2021 - 01/2021)
4.	Choi, Bu Young: 2 articles (01/2021 - 08/2019)
5.	Dong, Zigang: 2 articles (01/2021 - 08/2019)
6.	Yin, Fanxiang: 2 articles (01/2021 - 08/2019)
7.	Zhao, Ran: 2 articles (01/2021 - 08/2019)
8.	Chae, Jung-Il: 1 article (06/2021)
9.	Cho, Seung-Sik: 1 article (06/2021)
10.	Kwak, Ah-Won: 1 article (06/2021)

Related Diseases

1.	Human Influenza (Influenza) 06/01/2012 - "We previously reported that 3-deoxysappanchalcone (3-DSC), a compound that is isolated from Caesalpinia sappan, exhibited in vitro anti-influenza activity. " 06/01/2021 - "The 3-deoxysappanchalcone (3-DSC), a chemical separated from Caesalpinia sappan L, has been substantiated to display anti-inflammatory, anti-influenza, and anti-allergy activities according to previous studies. "
2.	Hypersensitivity (Allergy) 06/01/2021 - "The 3-deoxysappanchalcone (3-DSC), a chemical separated from Caesalpinia sappan L, has been substantiated to display anti-inflammatory, anti-influenza, and anti-allergy activities according to previous studies. " 07/01/2009 - "Among the compounds tested, sappanchalcone (2) possessed the most potent effect against allergic reaction in RBL-2H3 cells with an inhibitory concentration (IC50) value of 7.6 microM, followed by 3-deoxysappanchalcone (1, IC50 = 15.3 microM), whereas other compounds showed moderate and mild effects. "
3.	Skin Neoplasms (Skin Cancer) 01/01/2021 - "The present study investigates the role of 3-deoxysappanchalcone (3-DSC), a plant-derived functional TOPK inhibitor, in suppressing skin cancer cell growth. " 01/01/2021 - "3-Deoxysappanchalcone Inhibits Skin Cancer Proliferation by Regulating T-Lymphokine-Activated Killer Cell-Originated Protein Kinase in vitro and in vivo."
4.	Lung Neoplasms (Lung Cancer) 07/01/2023 - "The mechanistic functions of 3-deoxysappanchalcone (3-DSC), a chalcone compound known to have many pharmacological effects on lung cancer, have not yet been elucidated. " 07/01/2023 - "3-Deoxysappanchalcone Inhibits Cell Growth of Gefitinib-Resistant Lung Cancer Cells by Simultaneous Targeting of EGFR and MET Kinases."
5.	Inflammation (Inflammations) 06/01/2012 - "The protective effect of 3-deoxysappanchalcone on in vitro influenza virus-induced apoptosis and inflammation."

Related Drugs and Biologics

1.	Protein Kinases (Protein Kinase)
2.	Phosphotransferases (Kinase)
3.	Chalcone (Benzalacetophenone)
4.	Gefitinib (Iressa)
5.	sappanchalcone