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4-O-methylhonokiol

anti-inflammatory from Magnolia officinalis; structure in first source

Networked: 19 relevant articles (1 outcomes, 4 trials/studies)

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Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Biphenyl Compounds: 7
        4-O-methylhonokiol: 19
        Benzyl Compounds: 2
        Lignans: 1113
        4-O-methylhonokiol: 19

Experts

1.	Hong, Jin Tae: 10 articles (07/2015 - 07/2009)
2.	Kim, Ki Ho: 6 articles (01/2014 - 07/2009)
3.	Han, Sang Bae: 5 articles (07/2012 - 08/2009)
4.	Choi, Dong-Young: 4 articles (05/2014 - 01/2011)
5.	Lee, Young-Jung: 4 articles (05/2014 - 01/2011)
6.	Nam, Sang-Yoon: 4 articles (04/2014 - 07/2009)
7.	Kim, Young Heui: 4 articles (01/2014 - 07/2009)
8.	Cai, Lu: 3 articles (01/2019 - 01/2014)
9.	Kim, Kyoung Tae: 3 articles (01/2019 - 07/2009)
10.	Zhang, Zhiguo: 3 articles (01/2019 - 01/2014)

Related Diseases

1.	Type 2 Diabetes Mellitus (MODY) 01/01/2019 - "4-O-methylhonokiol ameliorates type 2 diabetes-induced nephropathy in mice likely by activation of AMPK-mediated fatty acid oxidation and Nrf2-mediated anti-oxidative stress."
2.	Neoplasms (Cancer) 03/01/2015 - "4-O-Methylhonokiol (MH), a bioactive compound derived from Magnolia officinalis, is known to exhibit antitumor effects in various cancer cells. " 07/01/2012 - "4-O-methylhonokiol inhibits colon tumor growth via p21-mediated suppression of NF-κB activity." 07/01/2012 - "4-O-methylhonokiol inhibited tumor growth, NF-κB activity and expression of antiapoptotic proteins; however, it increased the expression of apoptotic proteins as well as p21 in xenograft nude mice bearing SW620 cancer cells. " 07/01/2012 - "4-O-methylhonokiol (0-30 μM) decreased constitutive activated nuclear factor (NF)-κB DNA binding activity and inhibited growth of human colon (SW620 and HCT116) cancer cells. " 10/01/2012 - "The present study suggests that honokiol, magnolol and 4-O-methylhonokiol could be promising agents for reducing the multidrug resistance of cancer cells to anticancer drugs via the down-regulation of P-gp expression."
3.	Obesity 01/01/2014 - "In the present study, the preventive effect on high-fat diet- (HFD-) induced obesity and insulin resistance in mice by Magnolia bioactive constituent 4-O-methylhonokiol (MH) was compared with Magnolia officinalis extract BL153. " 01/01/2014 - "The magnolia bioactive constituent 4-O-methylhonokiol protects against high-fat diet-induced obesity and systemic insulin resistance in mice."
4.	Insulin Resistance 01/01/2014 - "In the present study, the preventive effect on high-fat diet- (HFD-) induced obesity and insulin resistance in mice by Magnolia bioactive constituent 4-O-methylhonokiol (MH) was compared with Magnolia officinalis extract BL153. " 01/01/2014 - "The magnolia bioactive constituent 4-O-methylhonokiol protects against high-fat diet-induced obesity and systemic insulin resistance in mice."
5.	Colonic Neoplasms (Colon Cancer) 07/01/2012 - "This study investigated the effects of 4-O-methylhonokiol (MH), a constituent of Magnolia officinalis, on human colon cancer cell growth and its action mechanism. "

Related Drugs and Biologics

1.	Fatty Acids (Saturated Fatty Acids)
2.	honokiol
3.	magnolol
4.	Scopolamine (Hyoscine)
5.	Ethanol (Ethyl Alcohol)
6.	Proteins (Proteins, Gene)
7.	Amyloid Precursor Protein Secretases (beta-Secretase)
8.	NF-kappa B (NF-kB)
9.	Amyloid (Amyloid Fibrils)
10.	AMP-Activated Protein Kinases