HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

N'- (4- bromo- 5- methyl- 2- oxoindolin- 3- ylidene)- 3,4,5- trimethoxybenzohydrazide

a potent apoptosis inducer; structure in first source

Also Known As:

BMOTH cpd

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrazines: 379
  - N'-(4-bromo-5-methyl-2-oxoindolin-3-ylidene)-3,4,5-trimethoxybenzohydrazide: 1

Experts

1.	Cai, Sui Xiong: 1 article (05/2009)
2.	Drewe, John: 1 article (05/2009)
3.	Pervin, Azra: 1 article (05/2009)
4.	Sirisoma, Nilantha: 1 article (05/2009)
5.	Tseng, Ben: 1 article (05/2009)

Related Diseases

1.

Colorectal Neoplasms (Colorectal Cancer)

05/15/2009 - "Through SAR studies, N'-(4-bromo-5-methyl-2-oxoindolin-3-ylidene)-3,4,5-trimethoxybenzohydrazide (3g) was identified as a potent apoptosis inducer with an EC(50) value of 0.24microM in human colorectal carcinoma HCT116 cells, more than a 40-fold increase in potency from the initial screening hit N'-(5-bromo-2-oxoindolin-3-ylidene)-3,4,5-trimethoxybenzohydrazide (2a). "