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S 35171

Antihypertensive Agent

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperazines: 26
    - Trimetazidine: 714
      - S 35171: 1

Experts

1.	Banfi, Cristina: 1 article (02/2009)
2.	Brioschi, Maura: 1 article (02/2009)
3.	Gelosa, Paolo: 1 article (02/2009)
4.	Gianella, Anita: 1 article (02/2009)
5.	Guerrini, Uliano: 1 article (02/2009)
6.	Nobili, Elena: 1 article (02/2009)
7.	Pignieri, Alice: 1 article (02/2009)
8.	Sironi, Luigi: 1 article (02/2009)
9.	Tremoli, Elena: 1 article (02/2009)

Related Diseases

1.	Stroke (Strokes) 02/14/2009 - "S 35171 exerts protective effects in spontaneously hypertensive stroke-prone rats by preserving mitochondrial function." 02/14/2009 - "We tested the hypothesis that S 35171 exerts protective effects in spontaneously hypertensive stroke-prone rats (SHRSPs), an animal model developing spontaneous brain damage preceded by proteinuria and systemic inflammation revealed by the urinary accumulation of acute-phase proteins (APPs) originating in the liver. "
2.	Proteinuria 02/14/2009 - "Male SHRSPs fed a permissive diet received vehicle or S 35171 (10 mg/kg/day) started simultaneously with a high-sodium diet (group A) or after the establishment of proteinuria (group B). " 02/14/2009 - "We tested the hypothesis that S 35171 exerts protective effects in spontaneously hypertensive stroke-prone rats (SHRSPs), an animal model developing spontaneous brain damage preceded by proteinuria and systemic inflammation revealed by the urinary accumulation of acute-phase proteins (APPs) originating in the liver. "
3.	Inflammation (Inflammations) 02/14/2009 - "We tested the hypothesis that S 35171 exerts protective effects in spontaneously hypertensive stroke-prone rats (SHRSPs), an animal model developing spontaneous brain damage preceded by proteinuria and systemic inflammation revealed by the urinary accumulation of acute-phase proteins (APPs) originating in the liver. "
4.	Hypertension (High Blood Pressure) 02/14/2009 - "Proteomic analysis showed no significant alteration in the expression pattern of brain mitochondrial proteins, but the liver mitochondrial levels of carbamoylphosphate synthase I (CPS-I), an enzyme involved in urea metabolism) and the antioxidant peroxiredoxin-3 spot were affected by hypertension and S 35171. "

Related Drugs and Biologics

1.	Acute-Phase Proteins (Acute-Phase Protein)
2.	Peroxiredoxin III
3.	Mitochondrial Proteins (Mitochondrial Protein)
4.	Urea (Carbamide)
5.	Sodium
6.	Glycogen Synthase (Synthase I)
7.	Enzymes
8.	Antioxidants