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5-formyl-pyrrole-2-carboxylic acid (1- (1- formyl- 3- methyl- butylcarbamoyl)- 2- methyl- propyl)amide

structure in first source

Also Known As:

CAT 0059; CAT-0059; CAT0059

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - 5-formyl-pyrrole-2-carboxylic acid (1-(1-formyl-3-methyl-butylcarbamoyl)-2-methyl-propyl)amide: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrroles: 369
      - 5-formyl-pyrrole-2-carboxylic acid (1-(1-formyl-3-methyl-butylcarbamoyl)-2-methyl-propyl)amide: 1

Experts

1.	Abell, Andrew D: 1 article (12/2008)
2.	Bickerstaffe, Roy: 1 article (12/2008)
3.	Coxon, James M: 1 article (12/2008)
4.	Jones, Matthew A: 1 article (12/2008)
5.	Lee, Hannah Y Y: 1 article (12/2008)
6.	McDermott, Joshua D: 1 article (12/2008)
7.	Mehrtens, Janna M: 1 article (12/2008)
8.	Morton, James D: 1 article (12/2008)
9.	Robertson, Lucinda J G: 1 article (12/2008)

Related Diseases

1.

Cataract (Cataracts)

12/01/2008 - "The two in vivo trials addressed the ability of CAT0059 to reach the lens and established its limitations as a therapeutic molecule for cataract treatment."
12/01/2008 - "The aim of this study is to evaluate the therapeutic potential of a newly synthesized calpain inhibitor, CAT0059, using a naturally occurring in vivo sheep cataract model. "
12/01/2008 - "However, application of CAT0059 in an eye ointment initially slowed cataract development compared with the untreated eye. "
12/01/2008 - "The 67-day CAT0059 eye drop treatment was not effective in slowing the rate of cataract development. "

Related Drugs and Biologics

1.	calpain inhibitors
2.	Ophthalmic Solutions (Eye Drops)
3.	Ointments (Pastes)