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cucumarioside A2-2

isolated from Cucumaria japonica; structure in first source

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - Saponins: 2867
    - cucumarioside A2-2: 5

Experts

1.	Aminin, D L: 2 articles (01/2015 - 01/2013)
2.	Menchinskaya, E S: 2 articles (01/2015 - 01/2013)
3.	Avilov, Sergey A: 2 articles (10/2013 - 02/2009)
4.	Stonik, Valentin A: 2 articles (10/2013 - 02/2009)
5.	Lapshina, L A: 1 article (01/2015)
6.	Pimenova, E A: 1 article (01/2015)
7.	Reunov, A A: 1 article (01/2015)
8.	Reunov, A V: 1 article (01/2015)
9.	Reunova, Yu A: 1 article (01/2015)
10.	Aminin, Dmitry L: 1 article (10/2013)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2013 - "The in vivo anticancer effect of cucumarioside A2-2 may be associated with the ability of the drug to arrest the cell cycle in the synthetic phase and induce programmed tumor cell death." 01/01/2013 - "Cucumarioside A2-2 influences tumor cell viability at micromolar concentrations. " 01/01/2013 - "The anticancer and proapoptotic properties of cucumarioside A2-2 may be due to direct interaction of the glycoside with tumor cells. " 10/01/2013 - "Inhibition of tumor cells multidrug resistance by cucumarioside A2-2, frondoside A and their complexes with cholesterol." 11/24/2023 - "Holothurian triterpene glycoside cucumarioside A2-2 induces macrophages activation and polarization in cancer immunotherapy."
2.	Carcinoma (Carcinomatosis) 01/01/2015 - "Cucumarioside A2-2 stimulates apoptotic necrosis in Ehrlich ascites carcinoma cells." 01/01/2013 - "The cytotoxicity of cucumarioside A2-2 and its effect on apoptosis, the cell cycle, DNA biosynthesis and p53 activity, and glycoside anticancer action against Ehrlich carcinoma cells were studied. "
3.	Necrosis 01/01/2015 - "Cucumarioside A2-2 stimulates apoptotic necrosis in Ehrlich ascites carcinoma cells."
4.	Leukemia 02/18/2009 - "Differential effects of triterpene glycosides, frondoside A and cucumarioside A2-2 isolated from sea cucumbers on caspase activation and apoptosis of human leukemia cells."
5.	Ascites 01/01/2015 - "Cucumarioside A2-2 stimulates apoptotic necrosis in Ehrlich ascites carcinoma cells."

Related Drugs and Biologics

1.	Glycosides
2.	Triterpenes
3.	frondoside A
4.	Caspases
5.	DNA (Deoxyribonucleic Acid)
6.	Cholesterol

Related Therapies and Procedures

1.	Immunotherapy