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AZX 100

a phosphopeptide analog of HSP20; amino acid sequence in first source

Also Known As:

AZX-100; AZX100

Networked: 4 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Phosphoproteins: 1772
    - AZX 100: 4
  - Molecular Chaperones: 1279
    - Heat-Shock Proteins: 8088
      - Small Heat-Shock Proteins: 401
        AZX 100: 4

Experts

1.	Brophy, Colleen M: 3 articles (07/2010 - 03/2009)
2.	Flynn, Charles R: 2 articles (07/2010 - 03/2009)
3.	Furnish, Elizabeth J: 2 articles (03/2010 - 03/2009)
4.	Arno, Anna I: 1 article (06/2014)
5.	Barret, Juan P: 1 article (06/2014)
6.	Gauglitz, Gerd G: 1 article (06/2014)
7.	Jeschke, Marc G: 1 article (06/2014)
8.	Cheung-Flynn, Joyce: 1 article (07/2010)
9.	Lowry, David: 1 article (07/2010)
10.	Roberson, Robert: 1 article (07/2010)

Related Diseases

1.	Cicatrix (Scar) 03/01/2009 - "Taken together, these results suggest the potential use of AZX100 as a strategy to prevent excessive scarring and fibrotic disorders." 03/01/2009 - "We also examined the effect of AZX100 on scar formation in vivo in dermal wounds in a Siberian hamster model. " 03/01/2009 - "In vivo, AZX100 significantly improved collagen organization in a Siberian hamster scarring model. "
2.	Keloid 03/01/2009 - "Treatment with AZX100 decreased stress fiber formation and altered the morphology of human dermal keloid fibroblasts. " 07/01/2010 - "Internalization and intracellular trafficking of a PTD-conjugated anti-fibrotic peptide, AZX100, in human dermal keloid fibroblasts." 03/01/2009 - "In the present study, we evaluated the effect of AZX100, a phosphopeptide analogue of HSP20, on transforming growth factor-beta-1 (TGF-beta1)-induced CTGF and collagen expression in human keloid fibroblasts. " 06/01/2014 - "Peptides such as the transforming growth factor beta (TGF-β) superfamily, with Smads, Ski, SnoN, Fussels, endoglin, DS-Sily, Cav-1p, AZX100, thymosin-β4 and other related molecules may emerge as targets to prevent and treat keloids and hypertrophic scars. "
3.	Hypertrophic Cicatrix (Hypertrophic Scar) 06/01/2014 - "Peptides such as the transforming growth factor beta (TGF-β) superfamily, with Smads, Ski, SnoN, Fussels, endoglin, DS-Sily, Cav-1p, AZX100, thymosin-β4 and other related molecules may emerge as targets to prevent and treat keloids and hypertrophic scars. "
4.	Wounds and Injuries (Trauma) 03/01/2009 - "We also examined the effect of AZX100 on scar formation in vivo in dermal wounds in a Siberian hamster model. "
5.	Hypotension (Low Blood Pressure) 03/01/2010 - "Intravenous administration of AZX100 also prevented and reversed decreases in cerebral perfusion at doses that did not induce hypotension. "

Related Drugs and Biologics

1.	Collagen
2.	Phosphopeptides
3.	Peptides (Polypeptides)
4.	Transforming Growth Factor beta (TGF-beta)
5.	Endoglin

Related Therapies and Procedures

1.	Intravenous Administration