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celebeside A

an anti-HIV agent isolated from the Indian sponge Siliquariaspongia mirabilis; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - Depsipeptides: 297
      - celebeside A: 1
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - Depsipeptides: 297
      - celebeside A: 1

Experts

1.	Baker, Heather L: 1 article (01/2009)
2.	Bewley, Carole A: 1 article (01/2009)
3.	Bifulco, Giuseppe: 1 article (01/2009)
4.	Keffer, Jessica L: 1 article (01/2009)
5.	Lloyd, John R: 1 article (01/2009)
6.	Plaza, Alberto: 1 article (01/2009)

Related Diseases

1.

Carcinoma (Carcinomatosis)

01/16/2009 - "Celebeside A neutralized HIV-1 in a single-round infectivity assay with an IC(50) value of 1.9 +/- 0.4 microg/mL while the nonphosphorylated analog celebeside C was inactive at concentrations as high as 50 microg/mL. Theopapuamides A-C showed cytotoxicity against human colon carcinoma (HCT-116) cells with IC(50) values between 2.1 and 4.0 microg/mL and exhibited strong antifungal activity against wildtype and amphotericin B-resistant strains of Candida albicans at loads of 1-5 microg/disk."

Related Drugs and Biologics

1.	Amphotericin B (Amphotericin)