Granulomatosis with Polyangiitis

A multisystemic disease of a complex genetic background. It is characterized by inflammation of the blood vessels (VASCULITIS) leading to damage in any number of organs. The common features include granulomatous inflammation of the RESPIRATORY TRACT and KIDNEYS. Most patients have measurable autoantibodies (ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES) against MYELOBLASTIN.

Also Known As:

Wegener's Granulomatosis; Granulomatosis with Polyangiitides; Granulomatosis, Wegener; Polyangiitides, Granulomatosis with; Polyangiitis, Granulomatosis with; with Polyangiitides, Granulomatosis; with Polyangiitis, Granulomatosis; Granulomatosis, Wegener's; Wegener Granulomatosis

Respiratory Tract Diseases: 6015
- Lung Diseases: 22246
  - Interstitial Lung Diseases: 8435
    - Granulomatosis with Polyangiitis: 2912
Cardiovascular Diseases: 91362
- Vascular Diseases: 15138
  - Vasculitis: 11851
    - Systemic Vasculitis: 1530
      - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis: 2538
        Granulomatosis with Polyangiitis: 2912
Skin and Connective Tissue Diseases
- Skin Diseases: 13127
  - Vascular Skin Diseases: 528
    - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis: 2538
      - Granulomatosis with Polyangiitis: 2912
Immune System Diseases: 4321
- Autoimmune Diseases: 34618
  - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis: 2538
    - Granulomatosis with Polyangiitis: 2912

Midline granulomatosis

Disease Context: Research Results