Rapidly progressive glomerulonephritis with pulmonary hemorrhage

01/01/1994 - "Although there have been reports of patients with pulmonary-renal syndrome in association with antiproteinase 3 antibodies in the absence of a well-known vasculitic disease, we have not so far seen a case documented by a detailed autopsy study such as is presented here. "
02/01/2019 - "Successful pregnancy in a patient with pulmonary renal syndrome double-positive for anti-GBM antibodies and p-ANCA
."
06/01/2005 - "Pulmonary renal syndrome is a rare event in childhood and coexistence of the two types of antibodies is exceptional."
01/04/2001 - "Rapidly progressive antineutrophil cytoplasm antibodies associated with pulmonary-renal syndrome in a 10-year-old girl."
08/01/1995 - "We evaluated the association as well as the diagnostic and the prognostic significance of these antibodies in pulmonary renal syndrome. "

12/01/2021 - "Imlifidase as novel treatment strategy in anti-neutrophil cytoplasmic antibody-induced pulmonary-renal syndrome."
01/06/2021 - "This case serves as an important clinical reminder to consider AAV even in those with negative ANCA serologies and a high suspicion for pulmonary-renal syndrome. "
01/01/2019 - "Characteristics and Outcomes of Patients with Anti-Glomerular Basement Membrane Antibody Disease and Anti-Neutrophil Cytoplasmic Antibodies."
03/01/2002 - "Delayed ANCA positivity in pulmonary-renal syndrome."
07/01/1996 - "We diagnosed pulmonary-renal syndrome associated with anti-neutrophil cytoplasmic antibody. "

07/01/2005 - "By accelerating the diagnosis of the specific underlying disease, autoantibody testing fosters rapid initiation of treatment and thereby significantly improved the prognosis of pulmonary-renal syndrome. "
01/01/2016 - "The diagnosis of pulmonary-renal syndrome was initially missed because of the absence of autoantibodies in all serological findings. "
10/01/2011 - "Goodpasture's disease accounts for 20% of all patients presenting with a pulmonary-renal syndrome and may be associated with detectable perinuclear antineutrophil cytoplasmic autoantibody positivity in up to a third of patients. "
08/01/1995 - "Circulating autoantibodies as serological markers in the differential diagnosis of pulmonary renal syndrome."
01/01/2021 - "We propose that pulmonary involvement of COVID-19 caused exposure of alveolar basement membranes leading to the production of high avidity autoantibodies by long-lived plasma cells, resulting in severe pulmonary renal syndrome. "

01/01/1999 - "Further 19 positive results were found in a group of 251 patients with other diseases: 1 of 4 pts with Churg-Strauss syndrome, 1 of 2 with pulmonary renal syndrome, 5 of 28 with connective tissue diseases, 1 of 21 with tuberculosis, 1 of 23 with sarcoidosis, 1 of 6 with histiocytosis, 3 of 11 with hypersensitivity pneumonitis, 1 (lymphoma) of 34 with neoplasms, 1 of 20 with pulmonary fibrosis, 1 of 8 with cardiac failure, 1 of 5 with pleural fluid, 1 of 10 pneumoconiosis and toxic reactions (after furagin), 1 of 6 with BOOP. "

01/01/2003 - "Studies of gene-targeted mice lacking specific FcgammaR have demonstrated that animals lacking activator FcgammaR on circulating leukocytes were protected from immune complex induced glomerular injury, both in models of systemic lupus erythematosus (SLE) and anti-glomerular basement membrane antibody disease. "
12/01/2007 - "Here, we present a patient who clinically presented with pulmonary-renal syndrome; the renal histology revealed post-infectious glomerulonephritis of immune complex origin. "
08/01/2023 - "IgA nephropathy (IgAN), characterized as immune complex-mediated glomerulonephritis, can occasionally manifest alongside the pulmonary-renal syndrome. "
08/01/2001 - "Fatal pulmonary-renal syndrome manifested with immune complex crescentic glomerulonephritis in a patient with MPO-ANCA seropositivity."
08/01/2001 - "We report here upon a case of life-threatening pulmonary-renal syndrome manifested simultaneously with immune complex GN and myeloperoxidase (MPO)-ANCA seropositivity. "

01/01/2013 - "This case presentation has important clinical implications because uncategorizable pulmonary-renal syndrome (PRS) without the presence of ANCAs and anti-GBM antibody is extremely rare and has high rates of morbidity and mortality. "
01/01/2013 - "Pulmonary-Renal Syndrome with Negative ANCAs and Anti-GBM Antibody."
03/01/2011 - "An unusual association of anti-GBM diseases and lupus nephritis presenting as pulmonary renal syndrome."
01/01/2021 - "Splenic Infarcts and Pulmonary Renal Syndrome in a Young Patient with Double-Positive Anti-GBM and ANCA-Associated Vasculitis."
02/01/2019 - "Antiglomerular basement membrane (anti-GBM) antibody disease is a rare condition causing pulmonary hemorrhage and necrotizing glomerulonephritis (pulmonary renal syndrome). "

06/18/2018 - "We present here the case of a 27-year-old immunocompetent patient who developed pulmonary-renal syndrome, manifested with lung cavitation, miliary nodules, and necrotizing glomerulonephritis accompanied by elevated titers of myeloperoxidase antibody. "
01/01/2016 - "Successful Treatment of Dual-Positive Anti-Myeloperoxidase and Anti-Glomerular Basement Membrane Antibody Vasculitis with Pulmonary-Renal Syndrome."
04/01/2016 - "We report a case of 63-year-old Chinese man, having a history of anti-myeloperoxidase (MPO) antibody anti-neutrophil cytoplasmic antibody (ANCA)-associated pulmonary-renal syndrome 9 years ago, presented with second episode of rapidly progressive glomerulonephritis (RPGN) and alveolar haemorrhage compatible with anti-glomerular basement membrane (GBM) disease. "
12/01/2001 - "Microscopic polyangiitis presenting as pulmonary-renal syndrome in a patient with long-standing diffuse cutaneous systemic sclerosis and antibodies to myeloperoxidase."
08/01/2001 - "We report here upon a case of life-threatening pulmonary-renal syndrome manifested simultaneously with immune complex GN and myeloperoxidase (MPO)-ANCA seropositivity. "

11/01/2022 - "Hydralazine-Associated Pulmonary-Renal Syndrome."
07/01/2012 - "Hydralazine-induced pulmonary-renal syndrome: a case report."
01/01/2021 - "There are several cases reported in the literature of hydralazine-induced ANCA associated vasculitis (AAV) that have pulmonary manifestations, also known as hydralazine- induced pulmonary-renal syndrome (PRS), a condition with a high risk of mortality. "
01/01/2021 - "Hydralazine-Induced ANCA Associated Vasculitis (AAV) Presenting with Pulmonary-Renal Syndrome (PRS): A Case Report with Literature Review."
12/01/2012 - "We report a case of hydralazine-induced vasculitis presenting as pulmonary renal syndrome with fatal outcome even after aggressive treatment. "

05/01/2014 - "A false-positive antineutrophil cytoplasmic antibody proteinase 3 test in a patient with pulmonary-renal syndrome."
01/01/2019 - "A presumptive diagnosis is often rendered without histopathology if concordant positivity of ANCA by indirect immunofluorescence (IIF) and ELISA assays, i.e., P-ANCA+/myeloperoxidase (MPO) Ab+ or C-ANCA+/proteinase-3 (PR3) Ab+, is documented in the context of pulmonary-renal syndrome or rapidly progressive glomerulonephritis. "
10/01/2021 - "A Rare Case of Pulmonary-Renal Syndrome With Triple-Seropositive for Myeloperoxidase-Anti-Neutrophil Cytoplasm Antibody (MPO-ANCA), Proteinase 3 (PR3)-ANCA and Anti-Glomerular Basement Membrane (GBM) Antibodies."
02/26/1996 - "Appropriate tests for antibodies to proteinase 3, antibodies to myeloperoxidase, and anti-GBM antibodies provide reliable guides for making a diagnosis in patients with this pulmonary renal syndrome."
01/01/2014 - "Hydralazine induces myeloperoxidase and proteinase 3 anti-neutrophil cytoplasmic antibody vasculitis and leads to pulmonary renal syndrome."

03/01/2016 - "The aim of this article is to raise awareness of this unusual cause of a pulmonary-renal syndrome, guiding physicians to recognize it as a potential complication, and to consider high-dose steroids in managing the condition. "
03/01/2016 - "We hypothesize that the cause of this pulmonary-renal syndrome was an immunological reaction to Campylobacter; and that the initiation of high-dose steroids was responsible for the rapid reversal of the patient's pulmonary and renal impairment. "
11/01/2012 - "Steroid pulse therapy was administered because of a strong suspicion of immune-mediated pulmonary renal syndrome. "
03/01/2006 - "He was also treated with plasmapheresis and steroids, as a diagnosis of pulmonary-renal syndrome was entertained early in the disease course, which was subsequently ruled out. "
10/01/2004 - "To our knowledge, this is the first reported case of transplacental transfer of MPO-ANCA resulting in pulmonary-renal syndrome that was successfully treated with high-dose steroid therapy and exchange transfusion."

04/25/2019 - "Pulmonary-renal syndrome was assumed, and induction therapy was initiated. "
01/01/2010 - "Many causes of the pulmonary renal syndrome have been defined, and therapy is directed at the underlying etiologic factor for the syndrome. "
05/01/1995 - "When a pulmonary renal syndrome is suspected however it is important to obtain histological confirmation of the diagnosis prior to initiating therapy. "
03/01/1989 - "We conclude that a pulmonary-renal syndrome is a common manifestation of diverse disorders which differ in their prognosis and therapy. "
07/01/1985 - "Therapy of anti-glomerular basement membrane antibody disease: analysis of prognostic significance of clinical, pathologic and treatment factors."

06/05/2001 - "Long-term outcome of anti-glomerular basement membrane antibody disease treated with plasma exchange and immunosuppression."
01/01/2015 - "Severe Uncompensated Metabolic Alkalosis due to Plasma Exchange in a Patient with Pulmonary-Renal Syndrome: A Clinician's Challenge."
10/01/2011 - "Plasma exchange may be considered for treatment of pulmonary renal syndrome or refractory pulmonary hemorrhage."
01/01/2007 - "Pulmonary-renal syndrome, diffuse pulmonary hemorrhage and glomerulonephritis, associated with Wegener's granulomatosis effectively treated with early plasma exchange therapy."
01/01/2023 - "Case Report: High-dose immunoglobulins prior to plasma exchange in severe pulmonary renal syndrome."

10/01/2016 - "A 35-year-old female with anti-glomerular basement membrane antibody disease required rescue vascular access for hemodialysis. "
10/01/2006 - "A case report of pulmonary-renal syndrome treated with continuous hemodiafiltration and hemodialysis."
01/01/2008 - "We report a patient with a pulmonary-renal syndrome and p-ANCA vasculitis who relapsed one year after starting hemodialysis treatment. "
01/01/2020 - "We present a 61-year-old male with FLT3-mutated acute myeloid leukemia treated with midostaurin who developed acute kidney injury requiring hemodialysis and pulmonary renal syndrome. "
01/01/2014 - "The patient, on hemodialysis, presented episodes of respiratory failure, which was interpreted as acute pulmonary edema, but a suspicion of ANCA-related pulmonary renal syndrome was raised. "

01/01/2023 - "The role of plasmapheresis in the pulmonary-renal syndrome."
03/01/2006 - "He was also treated with plasmapheresis and steroids, as a diagnosis of pulmonary-renal syndrome was entertained early in the disease course, which was subsequently ruled out. "
12/01/2009 - "Prompt plasmapheresis and concurrent pulse therapy with methylprednisolone effectively rescued his pulmonary-renal syndrome. "
04/01/2021 - "We hereby report a case of drug-induced vasculitis (DV) from isotretinoin exposure leading to life-threatening pulmonary-renal syndrome requiring immunosuppression and plasmapheresis. "
12/01/2009 - "Pulmonary-renal syndrome (PRS) associated with antineutrophil cytoplasmic antibodies (ANCA)-negative microscopic polyangiitis (MPA) is relatively rare, and the effects of plasmapheresis on these patients remain unclear. "

12/01/2021 - "Four months later, he was admitted with a severe acute pulmonary-renal syndrome (severe acute on chronic kidney failure with active sediment and proteinuria, and diffuse alveolar hemorrhage (DAH) requiring mechanical ventilation). "
07/01/1998 - "The patient was admitted with a pulmonary-renal syndrome with hemoptysis, rapidly progressive renal failure, and hypoxemia that required mechanical ventilation in the intensive care unit. "