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Synovitis granulomatous with uveitis and cranial neuropathies

Subscribe to New Research on Synovitis granulomatous with uveitis and cranial neuropathies

Also Known As:

Arthrocutaneouveal granulomatosis; Blau syndrome; Granulomatosis, familial juvenile systemic; Granulomatosis, familial, Blau type; Granulomatous inflammatory arthritis, dermatitis, and uveitis, familial; Jabs syndrome

Networked: 143 relevant articles (1 outcomes, 11 trials/studies)

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Bio-Agent Context: Research Results

Experts

1.	Martin, Tammy M: 13 articles (04/2012 - 10/2003)
2.	Rosenbaum, James T: 12 articles (06/2011 - 10/2003)
3.	Davey, Michael P: 10 articles (06/2011 - 10/2003)
4.	Punzi, Leonardo: 8 articles (01/2015 - 06/2005)
5.	Rose, Carlos D: 7 articles (06/2014 - 12/2005)
6.	Kanazawa, Nobuo: 7 articles (01/2014 - 02/2005)
7.	Planck, Stephen R: 7 articles (04/2010 - 10/2003)
8.	Rosenzweig, Holly L: 6 articles (05/2015 - 01/2008)
9.	Wouters, Carine H: 6 articles (06/2014 - 10/2006)
10.	Kambe, Naotomo: 6 articles (01/2014 - 02/2005)

Related Diseases

1.	Uveitis 09/01/2010 - "Blau syndrome should be considered in the differential diagnosis of childhood uveitis and the genetic analysis of the CARD15/NOD2 gene is helpful in the diagnosis." 05/01/2015 - "To determine whether patients with juvenile systemic granulomatous disease (JSGD) (Blau syndrome) and uveitis have a characteristic ocular phenotype. " 01/01/2015 - "The etiology of Autoimmune chronic uveitis (ACU) is still unknown; NOD2/CARD15 gene mutations are responsible for the Blau Syndrome and can induce uveitis in animal models. " 09/01/2013 - "Blau syndrome-associated uveitis and the NOD2 gene." 06/01/2011 - "The innate immune receptor NOD2 is a genetic cause of uveitis (Blau syndrome). "
2.	Sarcoidosis (Schaumann Disease) 04/01/2013 - "[The present and the prospect of study on Blau syndrome/early-onset sarcoidosis]." 12/01/2007 - "The aim of this study was to evaluate whether ethnic Danes with sarcoidosis have CARD15 mutations associated with Blau syndrome. " 11/01/2015 - "Role of NOD2 Pathway Genes in Sarcoidosis Cases with Clinical Characteristics of Blau Syndrome." 12/01/2014 - "Caveats and truths in genetic, clinical, autoimmune and autoinflammatory issues in Blau syndrome and early onset sarcoidosis." 06/01/2011 - "The genetic and immunophenotypic characteristics of a 3-year-old patient with Blau syndrome (BS), an early onset sarcoidosis caused by mutations in NOD2, were investigated. "
3.	Crohn Disease (Crohn's Disease) 10/31/2007 - "Recent studies have implicated Single Nucleotide Polymorphisms (SNPs) of the NOD2/CARD15 gene with the onset of several Inflammatory Bowel Disorders (Crohn's Disease, Blau syndrome) and the progression of several malignant diseases. " 12/01/2003 - "Together, studies on Nod2 (Card15) provide a conceptual link between inflammatory disorders, such as Crohn's disease and Blau syndrome, and bacterial sensing." 12/01/2014 - "Polymorphisms in NOD2 are the cause of the inflammatory disorder Blau syndrome and act as susceptibility factors for the inflammatory bowel condition Crohn's disease. " 08/01/2013 - "There are more than 100 NOD2 gene mutations, some of which have been linked to diseases such as Crohn disease, Blau syndrome, and NOD2-associated autoinflammatory disease (NAID). " 01/15/2013 - "Dysregulation of NOD2 signaling is associated with inflammatory diseases, such as Crohn's disease and Blau syndrome. "
4.	Arthritis (Polyarthritis) 01/01/2014 - "However, detailed information on arthritis in Blau syndrome on which the therapeutic strategy should be based on is lacking. " 01/01/2014 - "Arthritis is the most frequent manifestation of Blau syndrome, an autoinflammatory disorder caused by the genetic mutation of NOD2. " 12/01/2005 - "Blau syndrome and related genetic disorders causing childhood arthritis." 02/01/2005 - "These data suggest that sporadic granulomatous arthritis may in fact be the sporadic form of Blau syndrome, but arising from a spontaneous neomutation. " 02/01/2005 - "We investigated the hypothesis that an individual with sporadic early onset granulomatous arthritis may have a Blau syndrome mutation in CARD15/NOD2. "
5.	Cryopyrin-Associated Periodic Syndromes 02/01/2007 - "NALP3 and NOD2, which belong to a cytosolic subgroup of PRMs, dubbed Nod-like-receptors (NLRs), have been associated recently with inflammatory diseases, specifically Crohn's disease and Blau syndrome (NOD2) and familial cold autoinflammatory syndrome, Muckle-Wells syndrome and chronic infantile neurological cutaneous and articular syndrome (NALP3). " 02/01/2009 - "Taken together, these data suggest that in contrast to related IL-1beta-dependent autoinflammatory cryopyrinopathies, Blau syndrome is not mediated by excess IL-1beta or other IL-1 activity." 04/01/2007 - "Recent studies have described the genetic association of polymorphisms in NOD-like receptor genes with complex chronic inflammatory barrier diseases, such as Crohn's disease and asthma and with rare auto-inflammatory syndromes including familial cold urticaria, Muckle-Wells syndrome and Blau syndrome. " 12/01/2012 - "The term autoinflammatory syndromes includes a broad variety of disorders, including cryopyrin-associated periodic syndromes (CAPS) such as neonatal onset multisystem inflammatory disease (NOMID), familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), periodic fever syndromes, including familial Mediterranean fever (FMF), TNF receptor-1 associated periodic syndrome (TRAPS), and Blau syndrome. " 01/01/2007 - "Furthermore, mutations in the genes that encode these proteins have been associated with complex inflammatory disorders including Crohn's disease, asthma, familial cold urticaria, Muckle-Wells syndrome, and Blau syndrome. "

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8.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
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