Propping Zerres syndrome

Also Known As:

ADULT syndrome; Acro-dermato-ungual-lacrimal-tooth syndrome; Pigment anomaly ectrodactyly hypodontia

Networked: 15 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Stomatognathic Diseases: 705
- Tooth Diseases: 33
  - Tooth Abnormalities: 33
    - Anodontia: 374
      - Propping Zerres syndrome: 15
- Stomatognathic System Abnormalities
  - Tooth Abnormalities: 33
    - Anodontia: 374
      - Propping Zerres syndrome: 15
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Congenital Abnormalities: 25723
- Inborn Genetic Diseases: 11939
  - Genetic Skin Diseases: 47
    - Ectodermal Dysplasia: 505
      - Propping Zerres syndrome: 15
Body Regions
- Breast
  - Propping Zerres syndrome: 15
Skin and Connective Tissue Diseases
- Skin Diseases: 13127
Eye Diseases: 3522
- Lacrimal Apparatus Diseases: 709
  - Lacrimal Duct Obstruction: 672
    - Propping Zerres syndrome: 15
Signs and Symptoms Pathological Conditions
- Pathologic Processes: 10023
  - Pigmentation Disorders: 149
    - Propping Zerres syndrome: 15
- Anatomical Pathological Conditions
  - Malformed Nails: 54
    - Propping Zerres syndrome: 15
Musculoskeletal Diseases: 719
- Musculoskeletal Abnormalities: 43
  - Congenital Limb Deformities: 8
    - Propping Zerres syndrome: 15

Related Diseases

1.	Ectrodactyly-cleft lip-palate syndrome
2.	Conduct Disorder (Conduct Disorders)
3.	Wounds and Injuries (Trauma)
4.	Neoplasms (Cancer)
5.	Ectodermal Dysplasia (Aplasia Cutis Congenita)

Experts

1.	Engeland, Kurt: 2 articles (06/2010 - 05/2008)
2.	Kirschner, Ralf D: 2 articles (06/2010 - 05/2008)
3.	Müller, Gerd A: 2 articles (06/2010 - 05/2008)
4.	Brunner, Han G: 2 articles (08/2006 - 04/2002)
5.	van Bokhoven, Hans: 2 articles (08/2006 - 04/2002)
6.	Capozio, Giovanna: 1 article (01/2021)
7.	Delli Noci, Stefano: 1 article (01/2021)
8.	Manna, Raffaele: 1 article (01/2021)
9.	Massaro, Maria Grazia: 1 article (01/2021)
10.	Moccaldi, Beatrice: 1 article (01/2021)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Propping Zerres syndrome:

1.	ElementsIBA 11/01/2022 - "The present study combined three-dimensional (3D) motion capture with finite element simulation to reconstruct a real shaking adult syndrome (SAS) case and further explore the injury biomechanics of SAS. " 11/01/2011 - "Our findings, rather than extend the clinical spectrum of ADULT syndrome, suggest that cleft palate can no longer be considered an element for differential diagnosis for ADULT, EEC, and LMS. "
2.	Proteins (Proteins, Gene)FDA Link 05/01/2008 - "Mutant p63 proteins derived from EEC and ADULT syndrome patients cannot activate S100A2 transcription whereas SHFM-related mutants still can stimulate the S100A2 promoter. " 10/01/2019 - "Tumor protein p63 (TP63)-related disorders can be divided into at least six categories, including ectrodactyly-ectodermal dysplasia-cleft lip/palate syndrome 3 (EEC syndrome 3), ankyloblepharon-ectodermal defects-cleft lip/palate syndrome (AEC syndrome), acro-dermo-ungual-lacrimal-tooth syndrome (ADULT syndrome), limb-mammary syndrome (LMS), Rapp-Hodgkin syndrome (RHS) and split-hand/foot malformation 4 (SHFM4), and are all a result of heterozygous mutations of TP63. "
3.	DNA (Deoxyribonucleic Acid)IBA 08/20/2009 - "Mutation analysis of p63 gene in the first Chinese ADULT syndrome family was performed using direct DNA sequencing. " 04/01/2002 - "However, unlike mutations in EEC syndrome, the R298Q ADULT syndrome mutation does not impair DNA binding. "
4.	Arginine (L-Arginine)FDA Link 08/01/2006 - "Here, we report three new unrelated ADULT syndrome families, all with mutations of arginine 298. " 08/01/2006 - "Delineation of the ADULT syndrome phenotype due to arginine 298 mutations of the p63 gene." 02/01/2013 - "Only two amino-acid residues are known to be mutated amongst ADULT syndrome: asparagines 6 and arginine 298. "
5.	Transcription Factors (Transcription Factor)IBA 11/01/2010 - "ADULT syndrome is one of five such syndromes that result from mutations in TP63, encoding the transcription factor p63. "
6.	SteroidsIBA 01/01/2021 - "Colchicine and interleukin-1 inhibitors were used in the management of the steroid-resistant adult syndrome. "
7.	Retinaldehyde (Retinal)IBA 03/01/2000 - "The patient presented with the triad of injuries associated with the shaking of infants: retinal haemorrhages, subdural haematoma, and patterned bruising; this has been described as the shaken adult syndrome. "
8.	NucleotidesIBA 10/01/2005 - "Mutation analysis of TP63 showed a single nucleotide substitution, c.G518A, predicting a novel missense mutation, p.V114M in exon 4. This is the third mutation to be reported in TP63 in ADULT syndrome."
9.	Interleukin-1 (Interleukin 1)IBA 01/01/2021 - "Colchicine and interleukin-1 inhibitors were used in the management of the steroid-resistant adult syndrome. "
10.	Colchicine FDA LinkGeneric 01/01/2021 - "Colchicine and interleukin-1 inhibitors were used in the management of the steroid-resistant adult syndrome. "