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Noonan like syndrome

Also Known As:

Noonan Syndrome With Pigmented Villonodular Synovitis; Noonan-like-multiple giant cell lesion syndrome

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Musculoskeletal Diseases: 719
- Musculoskeletal Abnormalities: 43
  - Craniofacial Abnormalities: 203
    - Noonan Syndrome: 419
      - Noonan like syndrome: 3
- Jaw Diseases: 15
  - Giant Cell Granuloma: 294
    - Noonan like syndrome: 3
Stomatognathic Diseases: 705
- Mouth Diseases: 98
  - Periodontal Diseases: 9335
    - Gingival Diseases: 194
      - Giant Cell Granuloma: 294
        Noonan like syndrome: 3
- Jaw Diseases: 15
  - Giant Cell Granuloma: 294
    - Noonan like syndrome: 3
Signs and Symptoms Pathological Conditions
- Pathologic Processes: 10023
  - Granuloma: 11948
    - Giant Cell Granuloma: 294
      - Noonan like syndrome: 3
Cardiovascular Diseases: 91362
- Heart Diseases: 26014
  - Congenital Heart Defects: 8917
    - Noonan Syndrome: 419
      - Noonan like syndrome: 3
- Cardiovascular Abnormalities: 452
  - Congenital Heart Defects: 8917
    - Noonan Syndrome: 419
      - Noonan like syndrome: 3
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Congenital Abnormalities: 25723
  - Cardiovascular Abnormalities: 452
    - Congenital Heart Defects: 8917
      - Noonan Syndrome: 419
        Noonan like syndrome: 3
  - Musculoskeletal Abnormalities: 43
    - Craniofacial Abnormalities: 203
      - Noonan Syndrome: 419
        Noonan like syndrome: 3
Skin and Connective Tissue Diseases
- Connective Tissue Diseases: 3269
  - Noonan Syndrome: 419
    - Noonan like syndrome: 3

Experts

1.	Hahn, William C: 1 article (01/2021)
2.	Kwon, Jason J: 1 article (01/2021)
3.	Chen, Jie: 1 article (01/2020)
4.	Chen, Li: 1 article (01/2020)
5.	Cheng, Qian: 1 article (01/2020)
6.	Fan, Qiongli: 1 article (01/2020)
7.	Li, Tingyu: 1 article (01/2020)
8.	Liu, Yongfang: 1 article (01/2020)
9.	Yang, Ting: 1 article (01/2020)
10.	Zhang, Tianxiu: 1 article (01/2020)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Noonan like syndrome:

1.	Protein Phosphatase 1IBA 01/01/2020 - "Protein phosphatase 1 catalytic subunit beta (PPP1CB) is a disease-causing gene of Noonan-like syndrome, which acts via the RAS/MAPK pathway. "
2.	Mitogen-Activated Protein KinasesIBA 01/01/2021 - "Gain-of-function germ line mutations of SHOC2 drive the RASopathy Noonan-like syndrome, and SHOC2 mediates adaptive resistance to mitogen-activated protein kinase (MAPK) inhibitors. "
3.	Technetium Tc 99m MedronateIBA 12/01/2009 - "Aggressive noonan-like multiple giant cell lesion syndrome on Tc-99m MDP bone scan."