Sensory ataxic neuropathy, dysarthria, and ophthalmoparesis

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

1.	Ataxia Neuropathy Spectrum
2.	Mitochondrial Diseases (Mitochondrial Disease)
3.	Epilepsy (Aura)
4.	Diffuse Cerebral Sclerosis of Schilder (Alpers' Disease)
5.	Cerebellar Ataxia (Dysmetria)

Drugs and Important Biological Agents (IBA) related to Sensory ataxic neuropathy, dysarthria, and ophthalmoparesis:

1.	Mitochondrial DNA (mtDNA)IBA 01/01/2013 - "[A case of sensory ataxic neuropathy, dysarthria, and ophthalmoparesis with multiple mitochondrial DNA deletions]." 09/01/2003 - "The clinical findings of our patient is similar to that of SANDO (the triad of sensory ataxic neuropathy, dysarthria, and ophthalmoparesis), however, large mtDNA deletion reported by Fadic in patients with SANDO was not found in our patient. " 07/01/1997 - "The triad of sensory ataxic neuropathy, dysarthria, and ophthalmoparesis (SANDO) may represent a novel mitochondrial disease associated with multiple mitochondrial DNA deletions." 08/01/2006 - "ANT1, TWINKLE and POLG genes affect mtDNA stability and are involved in autosomal dominant PEO, while mutations in POLG are responsible for numerous clinical presentations, including autosomal recessive PEO, sensory ataxic neuropathy, dysarthria and ophthalmoparesis (SANDO), spino-cerebellar ataxia and epilepsy (SCAE) or Alpers syndrome. "
2.	DNA Polymerase gammaIBA 12/01/2021 - "Sensory ataxic neuropathy, dysarthria, and ophthalmoparesis (SANDO) is a rare mitochondrial disorder associated with mutations in the POLG gene, which encodes the DNA polymerase gamma catalytic subunit. "