Scleredema

01/01/1984 - "In one patient, the scleredema cleared without treatment, while in the other, the scleredema and the monoclonal gammopathy persisted unchanged."
03/01/1995 - "The presence of a monoclonal gammopathy in patients with chronic scleredema is a recently described, unusual association of unknown significance. "
03/01/1988 - "We assume, therefore, that the plasma cell dyscrasia was secondary to scleredema."
03/01/1988 - "In all patients, plasma cell dyscrasia appeared years after the onset of scleredema. "
03/01/1988 - "Review of the world literature enabled us to identify a statistically significant increased prevalence of plasma cell dyscrasia among patients with protracted scleredema. "

05/01/2000 - "Biomechanical measurement of skin distensibility in scleredema of Buschke associated with multiple myeloma."
07/01/1988 - "Scleredema of Buschke associated with multiple myeloma."
02/01/2006 - "The relationship of scleredema with paraprotein and multiple myeloma is well established, but only two cases of scleredema associated with amyloidosis have been reported to date. "
02/01/2006 - "We report the case of a 64-year-old lady with long-standing scleredema, associated with a paraprotein, and progressing to multiple myeloma and AL amyloidosis. "
01/01/1984 - "Two patients had scleredema with monoclonal gammopathy, one of whom was considered to have smoldering multiple myeloma. "

12/01/1986 - "Because differentiation of scleredema from scleredema neonatorum, subcutaneous fat necrosis, and scleroderma may be difficult, histologic diagnosis is important. "
06/01/2001 - "The items (including Delta-factors-that is, worsening according to the patient report) that were found to correlate with the gold standard on multiple regression were used to construct three separate 10-point indices of disease activity: (a) Delta-cardiopulmonary (4.0), Delta-skin (3.0), Delta-vascular (2.0), and Delta-articular/muscular (1.0) for patients with dSSc; (b) Delta-skin (2.5), erythrocyte sedimentation rate (ESR) >30 mm/1st h (2.5), Delta-cardiopulmonary (1.5), Delta-vascular (1.0), arthritis (1.0), hypocomplementaemia (1.0), and scleredema (0.5) for lSSc; (c) Delta-cardiopulmonary (2.0), Delta-skin (2.0), ESR >30 mm/1st h (1.5), total skin score >20 (1.0), hypocomplementaemia (1.0), scleredema (0.5), digital necrosis (0.5), Delta-vascular (0.5), arthritis (0.5), TLCO <80% (0.5) for all patients with SSc. "
07/01/2008 - "To review published literature on sclerema neonatorum (SN) in order to clarify its clinical presentation, histological features and management compared with two other diseases: subcutaneous fat necrosis of the newborn (SCFN) and scleredema. "

03/01/1995 - "Once chemotherapy for the myeloproliferative disorder was instituted, scleredema improved significantly, suggesting a pathogenetic link between the two conditions."

12/01/2001 - "After we had tried weekly LDL apheresis therapy for a period of 3 years to treat her hyperlipidemia, the levels of her serum lipids were reduced to normal ranges, and scleredema in her nape improved. "