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diffuse Mesangial sclerosis

Subscribe to New Research on diffuse Mesangial sclerosis

Also Known As:

Mesangial sclerosis, diffuse; Diffuse isolated mesangial sclerosis; Diffuse mesangial sclerosis; Familial mesangial sclerosis; Isolated diffuse mesangial sclerosis; Nephrotic syndrome, early onset with diffuse mesangial sclerosis

Networked: 111 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Ozaltin, Fatih: 4 articles (05/2014 - 03/2008)
2.	Gubler, Marie-Claire: 4 articles (07/2010 - 04/2005)
3.	Antignac, Corinne: 4 articles (07/2010 - 04/2005)
4.	Royer-Pokora, Brigitte: 3 articles (05/2015 - 06/2004)
5.	Hildebrandt, Friedhelm: 3 articles (07/2011 - 03/2008)
6.	Kopp, Jeffrey B: 3 articles (06/2009 - 05/2007)
7.	Barisoni, Laura: 3 articles (02/2009 - 09/2003)
8.	Zenker, Martin: 3 articles (04/2008 - 03/2006)
9.	Niaudet, Patrick: 3 articles (11/2006 - 03/2005)
10.	Neuhaus, Thomas J: 2 articles (05/2015 - 02/2011)

Related Diseases

1.	Wilms Tumor (Wilm's Tumor) 04/01/2005 - "WT1 mutations, causing Wilm's tumor, have been demonstrated in some CNS patients with diffuse mesangial sclerosis. " 03/01/2001 - "Isolated diffuse mesangial sclerosis and Wilms tumor suppressor gene." 11/01/1999 - "Although histopathological findings showed end-stage kidney, isolated diffuse mesangial sclerosis (IDMS) was suspected because of his clinical course, and was confirmed by the presence of WT1 (Wilms tumor suppressor gene) mutation. " 11/01/1999 - "In this study, two +KTS deletion mutants of WT1 were made as well as a WT1 mutant mimicking a mutation found in a patient who had diffuse mesangial sclerosis, end stage renal failure and Wilms tumor. " 10/01/2013 - "At 2 years of age, he has proteinuria and diffuse mesangial sclerosis, but no wilms tumor has been detected. "
2.	Chronic Kidney Failure (Chronic Renal Failure) 02/01/2006 - "Here we report two cases of isolated diffuse mesangial sclerosis (IDMS) with early onset end-stage renal failure. " 08/01/1992 - "A lethal polyadenopathic and visceral KS occurred in a 5-year-old Caribbean boy who had undergone an allogenic renal transplantation for diffuse mesangial sclerosis with end-stage renal failure 4 months previously. " 11/01/1999 - "In this study, two +KTS deletion mutants of WT1 were made as well as a WT1 mutant mimicking a mutation found in a patient who had diffuse mesangial sclerosis, end stage renal failure and Wilms tumor. " 01/01/2011 - "PI3KC2α-deficient mice developed chronic renal failure and exhibited a range of kidney lesions, including glomerular crescent formation and renal tubule defects in early disease, which progressed to diffuse mesangial sclerosis, with reduced podocytes, widespread effacement of foot processes, and modest proteinuria. " 04/01/2008 - "Diffuse mesangial sclerosis (DMS) is a histologically distinct variant of nephrotic syndrome (NS) that is characterized by early onset and by progression to end-stage kidney disease (ESKD). "
3.	Nephrotic Syndrome (Syndrome, Nephrotic) 05/01/2013 - "We present the 1st report of such an association in a boy who had a prenatal diagnosis of cystic lung malformation and was found to have congenital nephrotic syndrome (diffuse mesangial sclerosis) at 1 month of age. " 05/01/2012 - "Diffuse mesangial sclerosis (DMS) is a rare cause of nephrotic syndrome in the infantile and childhood period. " 08/01/2009 - "At the age of 15-months the patient developed nephrotic syndrome and renal biopsy indicated a histopathological diagnosis of diffuse mesangial sclerosis on histopathology. " 05/01/2009 - "Diffuse mesangial sclerosis (DMS) is a renal disease that usually presents as a nephrotic syndrome. " 02/01/2009 - "Here we describe three children from one consanguineous kindred of Pakistani origin with diffuse mesangial sclerosis who presented with congenital or infantile nephrotic syndrome. "
4.	Denys-Drash Syndrome 11/01/2006 - "Germline WT1 missense mutations located in exons 8 or 9 coding for zinc fingers 2 or 3 have been detected in nearly all patients with Denys-Drash syndrome and in some patients with isolated diffuse mesangial sclerosis. " 09/01/2004 - "While diffuse mesangial sclerosis is traditionally described as being the glomerulopathy of Denys-Drash syndrome (DDS), the podocyte proliferative lesions may be overlooked in these DDS cases. " 01/01/2003 - "The findings of the renal biopsy showed diffuse mesangial sclerosis, consistent with the characteristic change in Denys-Drash syndrome. " 03/01/2001 - "Diffuse mesangial sclerosis is a rare renal disease, occurring either in isolation or as part of Denys-Drash syndrome. " 05/01/2000 - "Absence of correlation between genotype and the severity of diffuse mesangial sclerosis in Denys-Drash syndrome."
5.	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 05/01/2014 - "Focal segmental glomerulosclerosis was equally prevalent in both cohorts, but diffuse mesangial sclerosis was largely specific for WT1 disease and was present in 34% of cases. " 04/01/2010 - "Sporadic cases of WT1 mutations in isolated diffuse mesangial sclerosis or focal segmental glomerulosclerosis have also been reported. " 07/01/2009 - "In the kidney, mutations in WT1 can cause diffuse mesangial sclerosis or focal segmental glomerulosclerosis. " 09/01/2003 - "The major podocytopathies can also be organized into four categories, including those with a normal glomerular histology, diffuse mesangial sclerosis, focal segmental glomerulosclerosis, and collapsing glomerulopathy." 01/01/1992 - "Renal biopsy revealed diffuse mesangial proliferation in 10 patients, diffuse mesangial sclerosis in 3, Finnish microcystic disease in 2, and focal segmental glomerulosclerosis and atypical glomerulopathy in 1 each. "

Related Drugs and Biologics

1.	Pierson syndrome
2.	Idiopathic minimal change nephrotic syndrome
3.	Finnish type Congenital nephrotic syndrome
4.	Collagen Type IV (Type IV Collagen)
5.	Transcription Factors (Transcription Factor)
6.	Staphylococcal Protein A (A, Protein)
7.	Immunoglobulin M (IgM)
8.	DNA (Deoxyribonucleic Acid)
9.	Dichlorodiphenyldichloroethane (DDD)
10.	Chondroitin

Related Therapies and Procedures

1.	Kidney Transplantation
2.	Nephrectomy