leucine-induced Hypoglycemia

A congenital metabolic disorder characterized by hypoglycemia following the consumption of LEUCINE-rich or high protein foods. It is caused by mutations in the SULFONYLUREA RECEPTORS (ABCC8) GENE. OMIM: 240800

Also Known As:

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Hypoglycemia (Reactive Hypoglycemia)

Experts

1.	Ganguly, Arupa: 1 article (09/2004)
2.	Katz, Lorraine E L: 1 article (09/2004)
3.	MacMullen, Courtney: 1 article (09/2004)
4.	Magge, Sheela N: 1 article (09/2004)
5.	Shyng, Show-Ling: 1 article (09/2004)
6.	Stanley, Charles A: 1 article (09/2004)
7.	Steinkrauss, Linda: 1 article (09/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to leucine-induced Hypoglycemia:

1.	Sodium Glutamate (Accent)IBA 12/01/1961 - "Effect of sodium glutamate on leucine-induced hypoglycemia: clinical and electroencephalographic study."
2.	Sulfonylurea ReceptorsIBA 09/01/2004 - "Familial leucine-sensitive hypoglycemia of infancy due to a dominant mutation of the beta-cell sulfonylurea receptor."
3.	Proteins (Proteins, Gene)FDA Link 09/01/2004 - "Familial leucine-sensitive hypoglycemia of infancy was described in 1956 as a condition in which symptomatic hypoglycemia was provoked by protein meals or the amino acid, leucine. "
4.	Phenytoin (Dilantin)FDA LinkGeneric 01/01/1984 - "Leucine-induced hypoglycemia in a family: effect of diphenylhydantoin, oxprenolol, and diazoxide."
5.	Oxprenolol (Trasicor)FDA Link 01/01/1984 - "Leucine-induced hypoglycemia in a family: effect of diphenylhydantoin, oxprenolol, and diazoxide."
6.	Leucine (L-Leucine)FDA Link 09/01/2004 - "Familial leucine-sensitive hypoglycemia of infancy was described in 1956 as a condition in which symptomatic hypoglycemia was provoked by protein meals or the amino acid, leucine. "
7.	Diazoxide (Hyperstat)FDA Link 01/01/1984 - "Leucine-induced hypoglycemia in a family: effect of diphenylhydantoin, oxprenolol, and diazoxide."
8.	Amino AcidsFDA Link 09/01/2004 - "Familial leucine-sensitive hypoglycemia of infancy was described in 1956 as a condition in which symptomatic hypoglycemia was provoked by protein meals or the amino acid, leucine. "