Littoral cell angioma of the spleen

Splenic vascular neoplasms that originate in the lining of the red pulp sinuses. Most cases are benign and asymptomatic; however, they may be associated with malignant neoplasms and hematologic disorders.

Also Known As:

Networked: 21 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Neoplasms (Cancer)
2.	Splenomegaly
3.	Sepsis (Septicemia)
4.	Wiskott-Aldrich Syndrome
5.	Thrombosis (Thrombus)

Experts

1.	Peng, Bing: 2 articles (01/2021 - 06/2015)
2.	Jhawar, Sachin R: 1 article (02/2022)
3.	Jones, Daniel: 1 article (02/2022)
4.	Perry, Kyle A: 1 article (02/2022)
5.	Yaney, Alexander: 1 article (02/2022)
6.	Karapolat, Banu: 1 article (10/2021)
7.	Kucuk, Hatice: 1 article (10/2021)
8.	Althoff, Christian E: 1 article (08/2021)
9.	Fischer, Thomas: 1 article (08/2021)
10.	Lerchbaumer, Markus Herbert: 1 article (08/2021)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Littoral cell angioma of the spleen:

1.	Propranolol (Inderal)FDA LinkGeneric 11/01/2016 - "Littoral cell angioma was preoperative suspicion owing to no response of the vascular lesion to the propranolol. "
2.	Factor VIII (Coagulation Factor VIII)IBA 11/01/2001 - "The tumours showed an immunohistochemical profile positive for factor VIII, CD31, CD68, cathepsin D, and CD21 and negative for CD34 and CD8, consistent with the immunophenotype of classic littoral cell angioma. "
3.	Cathepsin DIBA 11/01/2001 - "The tumours showed an immunohistochemical profile positive for factor VIII, CD31, CD68, cathepsin D, and CD21 and negative for CD34 and CD8, consistent with the immunophenotype of classic littoral cell angioma. "
4.	AntigensIBA 08/01/1994 - "The lack of expression of histiocytic antigens by the tumor endothelium is also evidence against a diagnosis of littoral cell angioma, which also derives from the sinus endothelium. "

Therapies and Procedures

1.	Splenectomy 08/01/2021 - "The patient underwent an open splenectomy with subsequent histopathologic and immunohistochemical studies that confirmed the presence of a littoral cell angioma of a diameter of 8 × 4.5 × 3.5 cm. " 10/01/2021 - "After histopathological and immunohistochemical analyses of the splenectomy material, he was diagnosed with Littoral cell angioma. " 01/01/2021 - "Laparoscopic Central Splenectomy for Littoral Cell Angioma." 03/01/2019 - "Laparoscopic splenectomy for littoral cell angioma of the spleen: A case report." 11/16/2015 - "Laparoscopic splenectomy for a littoral cell angioma of the spleen: Case report."
2.	Radiotherapy 02/07/2022 - "Rare case of littoral cell angioma recognised on CT simulation for adjuvant radiation treatment for early stage breast cancer."
3.	Injections 08/16/2021 - "While CT-guided biopsy revealed no results, CEUS-guided target biopsy with repeated contrast injections showed a benign littoral cell angioma of the spleen. "
4.	Renal Dialysis (Hemodialysis) 06/01/2006 - "Littoral cell angioma and splenic lipogranulomata in a renal dialysis patient with chronic left loin pain."