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Familial Testotoxicosis

Hereditary, GONADOTROPIN-independent, precocious puberty that occurs in boys before 4 years of age. It is associated with mutations in the LHCGR gene. OMIM: 176410
Also Known As:
Familial Gonadotrophin-Independent Sexual Precocity; Familial Male-Limited Precocious Puberty; Gonadotrophin-Independent Precocious Puberty; Precocious Pseudopuberty; Sexual precocity, familial, gonadotropin-independent; Testotoxicosis, Familial
Networked: 96 relevant articles (1 outcomes, 5 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Virilism (Virilization)
2. Precocious Puberty
3. Acne Vulgaris
4. Testicular Germ Cell Tumor
5. Granulosa cell tumor of the ovary

Experts

1. Narayan, Prema: 4 articles (01/2021 - 10/2013)
2. Latronico, Ana Claudia: 3 articles (07/2008 - 10/2003)
3. Hiremath, Deepak S: 2 articles (01/2021 - 05/2017)
4. Barnes, Kevin M: 2 articles (11/2017 - 01/2004)
5. Cutler, Gordon B: 2 articles (11/2017 - 01/2004)
6. Krone, Nils: 2 articles (11/2015 - 07/2006)
7. Arnhold, Ivo Jorge Prado: 2 articles (07/2008 - 04/2006)
8. Brito, Vinicius Nahime: 2 articles (07/2008 - 04/2006)
9. Mendonca, Berenice Bilharinho: 2 articles (07/2008 - 04/2006)
10. Chan, Wai-Yee: 2 articles (08/2006 - 02/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Familial Testotoxicosis:
1. 4-(fluoromethyl)phenyl phosphate (FMPP)IBA
2. Aromatase InhibitorsIBA
3. Androgen Antagonists (Antiandrogens)IBA
4. Luteinizing Hormone (Lutropin)FDA LinkGeneric
5. AndrogensIBA
6. Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric
7. Steroid 11-beta-Hydroxylase (11 beta-Hydroxylase)IBA
8. Gonadal Steroid Hormones (Sex Hormones)IBA
9. LH Receptors (LH Receptor)IBA
10. GonadotropinsIBA

Therapies and Procedures

1. Therapeutics
2. Off-Label Use