Temporomandibular ankylosis

A condition that occurs when the temporomandibular joint becomes fused by bony or fibrous tissue. It can interfere with speech, nutrition, oral hygiene and the normal growth of the face and/or jaw. It generally occurs during the first and second decades of life, and may be caused by trauma or infection. It is also associated with certain INFLAMMATION conditions such as ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; or PSORIASIS.

Also Known As:

Networked: 260 relevant articles (17 outcomes, 56 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Congenital Abnormalities (Deformity)
2.	Micrognathism
3.	Ankylosis
4.	Joint Diseases (Joint Disease)
5.	Foreign-Body Granuloma (Granuloma, Foreign Body)

Experts

1.	Mehrotra, Divya: 6 articles (10/2021 - 01/2009)
2.	Yang, Chi: 5 articles (11/2021 - 05/2012)
3.	Zhu, Songsong: 4 articles (01/2019 - 12/2012)
4.	Guarda-Nardini, Luca: 4 articles (07/2017 - 10/2008)
5.	Manfredini, Daniele: 4 articles (07/2017 - 10/2008)
6.	Bhutia, Ongkila: 3 articles (01/2022 - 07/2014)
7.	Roychoudhury, Ajoy: 3 articles (01/2022 - 07/2014)
8.	He, Dongmei: 3 articles (11/2021 - 01/2008)
9.	Li, Yunfeng: 3 articles (01/2019 - 09/2017)
10.	Zhang, Y: 3 articles (08/2018 - 12/2012)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Temporomandibular ankylosis:

1.	Hemoglobins (Hemoglobin)IBA 02/01/2018 - "This study was an attempt to find a relation between the hemoglobin and hematocrit values in TMJ ankylosis patients so that the clinical treatment and management of such patients during surgeries be improved and may be beneficial for the patient. "
2.	baysilon (polydimethylsiloxane)IBA 01/01/1968 - "Temporomandibular ankylosis corrected by creating a false silastic sponge fossa." 01/01/2002 - "In our opinion the gold standard surgery of TMJ ankylosis today is represented by shaving of articular surfaces and subsequent arthroplasty with or without temporal muscle myofascial flap interposition, whereas the use of Silastic as alloplastic material could be associated to an increased persistence of the local symptoms and a higher risk of foreign body granuloma and it may favor ankylosis relapse and hinder rehabilitation." 04/01/2006 - "We treated TMJ ankylosis with alloplastic medical grade silicone "silastic" interpositional arthroplasty. "
3.	Dioctyl Sulfosuccinic Acid (DOSS)IBA 08/01/2014 - "The preoperative fabrication of DOSs compared with the intraoperative fabrication of COSs resulted in a shorter treatment time and improved mandibular deviation correction in the treatment of children with unilateral TMJ ankylosis."
4.	2-benzyl-3-formylpropanoic acid (BFP)IBA 04/01/2012 - "On the basis of the findings of this study, we conclude that after release of TMJ ankylosis, reconstruction with SCG combined with interposition of BFP lining followed by vigorous physiotherapy is a successful strategy for the management of TMJ ankylosis with short-term follow-up of 6 months." 04/01/2012 - "To evaluate the feasibility of sternoclavicular graft (SCG) as an adaptive center along with buccal fat pad (BFP) lining for temporomandibular joint (TMJ) reconstruction in TMJ ankylosis. " 06/01/2019 - "The objective of this study was to highlight the role of lateral arthroplasty along with interposition of the buccal fat pad (BFP) in the management of Sawhney type III temporomandibular joint (TMJ) ankylosis. " 06/01/2019 - "Ten patients with TMJ ankylosis (7 unilateral and 3 bilateral, total of 13 joints) were treated with lateral arthroplasty and BFP interposition. " 01/01/2022 - "In this study, masticatory function was evaluated by measuring maximum voluntary bite force (MVBF) and chewing efficiency in 30 unilateral TMJ ankylosis patients who were treated with buccal fat pad (BFP) interpositional arthroplasty. "
5.	Durapatite (Hydroxylapatite)IBA 09/01/2017 - "This study was designed with the aim to assess the efficiency of hydroxyapatite/collagen (HA/Col) bio-scaffold with bone marrow aspirate (BMA) to reconstruct mandibular condyle in patients with temporomandibular joint (TMJ) ankylosis. " 12/01/2012 - "The aim of this study was to evaluate the feasibility of using preshaped hydroxyapatite/collagen condyles as carriers for platelet-rich plasma after gap arthroplasty in patients with temporomandibular ankylosis, to assess the aesthetic and functional outcomes, and to find out if neocondylar regeneration was possible. "
6.	CollagenIBA 09/01/2017 - "This study was designed with the aim to assess the efficiency of hydroxyapatite/collagen (HA/Col) bio-scaffold with bone marrow aspirate (BMA) to reconstruct mandibular condyle in patients with temporomandibular joint (TMJ) ankylosis. " 12/01/2012 - "The aim of this study was to evaluate the feasibility of using preshaped hydroxyapatite/collagen condyles as carriers for platelet-rich plasma after gap arthroplasty in patients with temporomandibular ankylosis, to assess the aesthetic and functional outcomes, and to find out if neocondylar regeneration was possible. "
7.	Anesthetics (Anesthetic Agents)IBA 01/01/2016 - "A total of 48 cases with radiographically and clinically confirmed cases of temporomandibular joint (TMJ) ankylosis were included in the study for evaluation of anesthetic management and its complications. " 05/04/2021 - "TMJ ankylosis impacts airway management, and anesthesia providers must be aware of this clinical phenotype when planning the anesthetic care of patients with Goldenhar syndrome."
8.	Type A Botulinum Toxins (Botox)FDA Link 01/01/2020 - "The aim of the present study was to determine the effect of intramuscular injection of botulinum toxin A (BTX-A) into the masticatory muscles on the physiotherapy pain and mouth opening outcomes after surgical intervention of temporomandibular joint (TMJ) ankylosis and to verify the effects using electromyographic studies. "
9.	Triamcinolone Acetonide (Azmacort)FDA LinkGeneric 01/01/2013 - "The findings of this study showed successful management of TMJ ankylosis using absorbable gelatin sponge soaked in triamcinolone acetonide in cases which did not require condylar reconstruction." 01/01/2013 - "To evaluate the feasibility and usefulness of absorbable gelatin sponge soaked in triamcinolone acetonide as an interposition material in the treatment of temporomandibular joint (TMJ) ankylosis. "
10.	Lidocaine (Xylocaine)FDA LinkGeneric 06/01/2015 - "Sixty adult patients with TMJ ankylosis were randomly assigned to the following study groups using a computer generated random number table 2 % lignocaine nebulised (group A) and 2 % lignocaine via spray-as-you-go technique (group B). " 06/01/2015 - "This randomized, comparative clinical study was designed to compare 2 % lignocaine nebulization and 2 % lignocaine via spray-as-you-go technique for topical airway anaesthesia during or awake flexible fiberoptic intubation (AFOI) in temporomandibular joint (TMJ) ankylosis patients. "

Therapies and Procedures

1.	Arthroplasty 01/01/2006 - "Gap arthroplasty showed good results when treating TMJ ankylosis." 12/01/2010 - "This study sought to determine the efficacy of interpositional arthroplasty with temporalis muscle and fascia flap in the treatment of unilateral temporomandibular joint (TMJ) ankylosis in adults. " 02/01/2005 - "This study aims to determine the efficacy of arthroplasty and interpositional fascia flap in the treatment of unilateral and bilateral TMJ ankylosis in three young adult men. " 06/01/2001 - "This study sought to determine the efficacy of interpositional arthroplasty with temporalis muscle and fascia flap in the treatment of unilateral temporomandibular joint (TMJ) ankylosis in adults. " 12/01/2021 - "The study concludes that distraction followed by arthroplasty was a better procedure for the management of TMJ ankylosis owing to its stable results and less number of surgeries."
2.	Distraction Osteogenesis 01/01/2018 - "Mandibular distraction osteogenesis (DO) has been shown to lead to considerable improvement in obstruction of the posterior airway space in patients with ankylosis of the temporomandibular joint (TMJ), and our objective was to find out if we could confirm these findings. " 07/01/2009 - "Distraction osteogenesis is an effective reconstruction method for TMJ ankylosis, matching the gold standard of costochondral grafting." 05/01/2020 - "This study aimed to evaluate the remodeling of condyles reconstructed by transport distraction osteogenesis (DO) in patients with temporomandibular joint (TMJ) ankylosis. " 09/01/2017 - "This study aimed to compare the joint function and morphology achieved following condylar reconstruction using sternoclavicular grafts (SCG) versus transport distraction osteogenesis (TDO) in temporomandibular joint (TMJ) ankylosis patients. " 06/01/2014 - "Thus the study was indigenously designed and aimed at qualitative evaluation of the functional and esthetic outcome after correction of mandibular hypoplasia secondary to temporomandibular ankylosis with Distraction osteogenesis. "
3.	Prostheses and Implants (Prosthesis) 11/01/2021 - "The purpose of this study was to determine whether the upper airway can be improved after TMJ reconstruction with total TMJ prostheses combined with or without MA in TMJ ankylosis patients. " 01/01/2017 - "This study evaluated the prognosis of using standard alloplastic TMJ prostheses for the treatment of TMJ ankylosis in Chinese patients with severe mandibular deficiency. " 03/01/2013 - "The purpose of this study was to evaluate the functional outcomes in patients affected by bilateral temporomandibular joint (TMJ) ankylosis treated with TMJ total alloplastic reconstruction with stock prosthesis. " 08/01/2023 - "Custom alloplastic TMJ prostheses are considered an optimal treatment modality for reconstructing the TMJ in adult patients with TMJ ankylosis." 08/01/2023 - "Thus, custom alloplastic TMJ prostheses have emerged as the preferred treatment modality for adult TMJ ankylosis. "
4.	Joint Prosthesis 07/01/2022 - ": In this case, stock TMJ total joint prostheses were used successfully to treat bilateral TMJ ankylosis following previous surgery for mandibular distraction." 07/01/2023 - "The patient underwent bilateral TMJR with a custom joint prosthesis for recurrent TMJ ankylosis. " 11/01/2021 - "Release of TMJ ankylosis and condylar reconstruction using total joint prostheses simultaneously with MA could significantly improve the total volume and other various parameters of the upper airway, while, only the dimension of the palatopharynx increased in cases without MA." 06/01/2016 - "To measure and identify factors associated with treatment outcomes for patients with temporomandibular joint (TMJ) ankylosis treated with TMJ Concepts patient-fitted total joint prostheses and autogenous fat grafts. " 06/01/2016 - "This retrospective cohort study evaluated records of patients with TMJ ankylosis from a single private practice, treated from 1992 to 2011, who met the following inclusion criteria: 1) radiographic evidence of bony ankylosis, 2) limited incisal opening, 3) minimum of 12 months' follow-up, and 4) treatment with TMJ Concepts (Ventura, CA)/Techmedica (Camarillo, CA) total joint prostheses and fat grafts. "
5.	Aftercare (After-Treatment) 08/01/2015 - "This study aimed to analyze cases of mandibular condylar fracture complicated by TMJ ankylosis after treatment. " 06/01/2017 - "Despite new guidelines and updated methods, treating patients with TMJ Ankylosis remains a challenge as the incidence of recurrence after treatment is soaring. " 02/01/2005 - "To evaluate the efficacy of temporal fascia as interpositioning material after treatment of TMJ ankylosis with gap arthroplasty. "