Hurthle cell Thyroid cancer

An ADENOMA or CARCINOMA that originates from the follicular cells of the THYROID GLAND. Cells exhibit large oncocytic morphology and abundant granular eosinophilic cytoplasm. Germline mutations in the NDUFA13 gene and somatic mutations in the RAS gene have been identified. OMIM: 607464

Also Known As:

Networked: 11 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Neoplasms (Cancer)
2.	Thyroid Neoplasms (Thyroid Cancer)
3.	Papillary Thyroid Cancer
4.	follicular Thyroid cancer
5.	Anaplastic Thyroid Carcinoma

Experts

1.	Butt, Muhammad Imran: 1 article (04/2021)
2.	Khalid Bakhsh, Abdulmohsen Mohammed: 1 article (04/2021)
3.	Nadri, Quaid Johar: 1 article (04/2021)
4.	Aygun, Nurcihan: 1 article (01/2021)
5.	Isgor, Adnan: 1 article (01/2021)
6.	Kostek, Mehmet: 1 article (01/2021)
7.	Uludag, Mehmet: 1 article (01/2021)
8.	Campisi, G: 1 article (12/2019)
9.	Mauceri, R: 1 article (12/2019)
10.	Morreale, I: 1 article (12/2019)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hurthle cell Thyroid cancer:

1.	lenvatinibIBA 04/24/2021 - "Lenvatinib-induced multiorgan adverse events in Hurthle cell thyroid cancer: A case report." 12/01/2019 - "A 58-year-old man diagnosed with Hurthle cell thyroid cancer, who was undergoing treatment with lenvatinib, developed maxillary osteonecrosis after a dental extraction. "
2.	RadiopharmaceuticalsIBA 06/01/1993 - "In a patient with metastatic Hurthle cell carcinoma of the thyroid, a subgroup of follicular carcinoma, scintigraphy with pentavalent 99mTc-labeled dimercaptosuccinic acid (V)DMSA showed a significant uptake of the radiopharmaceutical in all tumor sites. "
3.	Technetium Tc 99m Sestamibi (Cardiolite)FDA LinkGeneric 07/01/1992 - "Technetium-99m-sestamibi uptake by recurrent Hurthle cell carcinoma of the thyroid." 07/01/1992 - "Scintigraphic results for a patient with recurrent Hurthle cell carcinoma of the thyroid whose tumor was imaged with both 99mTc-sestamibi and 201TI, but not with 131I, are presented."
4.	Thyroid HormonesIBA 01/01/2018 - "The following words were used for a comprehensive literature review using MEDLINE database: Blood coagulation factors; thyroid hormones; blood coagulation tests; venous thromboembolism; receptors thyroid hormone; hemostasis; fibrinolysis; bleeding; blood coagulation disorders; thyroid neoplasms; Thyroid cancer, papillary; Thyroid cancer, follicular; Thyroid carcinoma, anaplastic; Thyroid cancer, Hurthle cell; Familial medullary thyroid carcinoma; venous thrombosis; Pulmonary embolism; Blood coagulation factors. "
5.	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 09/01/2011 - "Tc-99m- and Ga-68-labeled somatostatin analogues in the evaluation of Hurthle cell thyroid cancer."
6.	Thyroid Hormone Receptors (Thyroid Hormone Receptor)IBA 01/01/2018 - "The following words were used for a comprehensive literature review using MEDLINE database: Blood coagulation factors; thyroid hormones; blood coagulation tests; venous thromboembolism; receptors thyroid hormone; hemostasis; fibrinolysis; bleeding; blood coagulation disorders; thyroid neoplasms; Thyroid cancer, papillary; Thyroid cancer, follicular; Thyroid carcinoma, anaplastic; Thyroid cancer, Hurthle cell; Familial medullary thyroid carcinoma; venous thrombosis; Pulmonary embolism; Blood coagulation factors. "
7.	IodineIBA 05/01/2014 - "Follicular and Hurthle cell carcinoma of the thyroid in iodine-sufficient area: retrospective analysis of Korean multicenter data."
8.	Succimer (Dimercaptosuccinic Acid)FDA Link 06/01/1993 - "In a patient with metastatic Hurthle cell carcinoma of the thyroid, a subgroup of follicular carcinoma, scintigraphy with pentavalent 99mTc-labeled dimercaptosuccinic acid (V)DMSA showed a significant uptake of the radiopharmaceutical in all tumor sites. "
9.	Capsules (Microcapsules)IBA 08/01/2017 - "Confirmation by a pathologist of the diagnosis of a primary Hurthle cell carcinoma of the thyroid based on ≥75% Hurthle cells with extension through the tumor capsule. "
10.	Calcitonin (Calcitonin, Eel)FDA LinkGeneric 01/01/2005 - "Elevated basal calcitonin levels in a patient with a hurthle-cell carcinoma of the thyroid and neuroendocrine differentiation: report of a case."

Therapies and Procedures

1.	Thyroidectomy 04/24/2021 - "We report the case of a 47-year-old female with Hurthle cell thyroid cancer who underwent total thyroidectomy followed by radioiodine ablation. " 08/01/2017 - "Our experience suggests that the outcome of Hurthle cell carcinoma of the thyroid is favorable in adults with stage T1-3 NX-1b M0 disease who are managed with total thyroidectomy, radioiodine, and-in selected cases-external-beam radiotherapy. " 08/01/2017 - "Favorable Outcome of Hurthle Cell Carcinoma of the Thyroid Treated With Total Thyroidectomy, Radioiodine, and Selective Use of External-Beam Radiotherapy." 05/27/2008 - "We report a 77 year old lady who had total thyroidectomy and bilateral neck dissection followed by radiotherapy for a high grade metastatic Hurthle cell carcinoma of the thyroid. "
2.	Radiotherapy 08/01/2017 - "Our experience suggests that the outcome of Hurthle cell carcinoma of the thyroid is favorable in adults with stage T1-3 NX-1b M0 disease who are managed with total thyroidectomy, radioiodine, and-in selected cases-external-beam radiotherapy. " 08/01/2017 - "Favorable Outcome of Hurthle Cell Carcinoma of the Thyroid Treated With Total Thyroidectomy, Radioiodine, and Selective Use of External-Beam Radiotherapy." 05/27/2008 - "We report a 77 year old lady who had total thyroidectomy and bilateral neck dissection followed by radiotherapy for a high grade metastatic Hurthle cell carcinoma of the thyroid. "
3.	Neck Dissection (Radical Neck Dissection) 05/27/2008 - "We report a 77 year old lady who had total thyroidectomy and bilateral neck dissection followed by radiotherapy for a high grade metastatic Hurthle cell carcinoma of the thyroid. "