Trichofolliculoma

split away Congenital trichofolliculoma; and Sebaceous trichofolliculoma

Also Known As:

Congenital trichofolliculoma; Folliculo-sebaceous cystic hamartoma; Folliculosebaceous cystic hamartoma; Recurrent trichofolliculoma; Sebaceous trichofolliculoma

Networked: 16 relevant articles (0 outcomes, 3 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Steatocystoma Multiplex
2.	Epidermal Cyst (Sebaceous Cyst)
3.	Cysts
4.	Neoplasms (Cancer)
5.	Pilomatrixoma

Experts

1.	Beato, Maria Jose: 1 article (01/2020)
2.	Blei, Francine: 1 article (01/2020)
3.	Davies, Olivia M T: 1 article (01/2020)
4.	Drolet, Beth A: 1 article (01/2020)
5.	Fairley, Janet: 1 article (01/2020)
6.	Frieden, Ilona J: 1 article (01/2020)
7.	Galligan, Eloise R: 1 article (01/2020)
8.	Garzon, Maria C: 1 article (01/2020)
9.	Goddard, Deborah: 1 article (01/2020)
10.	Howard, Renee: 1 article (01/2020)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Trichofolliculoma:

1.	Keratins (Keratin)IBA 02/01/2009 - "Folliculosebaceous cystic hamartoma differentiates toward the infundibulum, sebaceous duct and sebaceous cells: immunohistochemical study of keratins and filaggrin." 01/01/2016 - "Immunohistochemical localization of keratins 1, 10 and 14, p63, and β-catenin in trichofolliculoma, trichoblastoma, and pilomatricoma, as well as keratoacanthoma, may indicate tumor histogenesis."
2.	Keratin-19 (Keratin 19)IBA 12/01/2019 - "We experienced a rare case of HFN on the neck of a 14-year-old boy and performed a pilot immunohistochemical study with cytokeratin 19 (CK19) to compare the staining pattern of hair follicles in HFN and its differential diagnoses, accessory tragus, cervical chondrocutaneous branchial remnants (CCBR) and trichofolliculoma. "
3.	Advanced Glycation End ProductsIBA 01/01/2004 - "Immunohistochemical studies using monoclonal anti-AGE (advanced glycation end product) antibody demonstrated that keratinous materials within the cystic structures were immunoreactive to the antibody, whereas those of cystic lesions (epidermal cyst, eruptive vellus hair cyst, steatocystoma multiplex, trichofolliculoma and trichilemmal cyst) seen in otherwise healthy individuals were negative. "
4.	Filaggrin ProteinsIBA 02/01/2009 - "Folliculosebaceous cystic hamartoma differentiates toward the infundibulum, sebaceous duct and sebaceous cells: immunohistochemical study of keratins and filaggrin."
5.	CateninsIBA 08/01/2011 - "β-Catenin expression in 48 adnexal tumors (trichoepithelioma, trichofolliculoma, pilomatricoma, syringoma, eccrine poroma, spiradenoma, sebaceous hyperplasia and nevus sebaceus) was assessed using immunohistochemistry. " 07/15/2014 - "Here, we show that chromatin effector Pygopus homolog 2 (Pygo2) produced by the epithelial cells facilitates depilation-induced hair regeneration, as well as β-catenin-induced activation of hair follicle stem/early progenitor cells and trichofolliculoma-like skin hyperplasia. " 01/01/2016 - "Immunohistochemical localization of keratins 1, 10 and 14, p63, and β-catenin in trichofolliculoma, trichoblastoma, and pilomatricoma, as well as keratoacanthoma, may indicate tumor histogenesis."
6.	Connexin 43 (Connexin43)IBA 11/01/2019 - "In 3 tumors (trichofolliculoma, pilomatrixoma, and the spectrum fibrofolliculoma/trichodiscoma), there was a parallelism between their Cx43 expression pattern and that of their alleged anatomical counterparts. "
7.	Acitretin FDA Link 10/01/2007 - "Giant genital variant of folliculosebaceous cystic hamartoma: successful management by CO2 laser and acitretin therapy."
8.	Cadherins (E-Cadherin)IBA 12/14/2011 - "Inhibition of BMP signaling in P-Cadherin positive hair progenitor cells leads to trichofolliculoma-like hair follicle neoplasias."
9.	SteroidsIBA 12/01/1997 - "Complete primary excision of trichofolliculoma is important, and local steroid preparations should not be used."
10.	Proteins (Proteins, Gene)FDA Link 01/01/2002 - "We show that HA is accumulated in the stroma of the cutaneous myxoma lesions and that the protein expression of CD44 in the keratinocytes of the trichofolliculoma-like epithelial buds projecting from the hair follicle centering these lesions is significantly decreased. "

Therapies and Procedures

1.	Gas Lasers 10/01/2007 - "Giant genital variant of folliculosebaceous cystic hamartoma: successful management by CO2 laser and acitretin therapy."
2.	Minimally Invasive Surgical Procedures 03/01/2023 - "We describe a case of a trichofolliculoma treated with a conscious, minimally invasive surgical procedure utilizing injectable lidocaine as local anesthetic, with no complications and excellent cosmetic results."
3.	Therapeutics 10/01/2007 - "Giant genital variant of folliculosebaceous cystic hamartoma: successful management by CO2 laser and acitretin therapy."
4.	Injections 03/01/2023 - "We describe a case of a trichofolliculoma treated with a conscious, minimally invasive surgical procedure utilizing injectable lidocaine as local anesthetic, with no complications and excellent cosmetic results."
5.	Hair Removal (Depilation) 07/15/2014 - "Here, we show that chromatin effector Pygopus homolog 2 (Pygo2) produced by the epithelial cells facilitates depilation-induced hair regeneration, as well as β-catenin-induced activation of hair follicle stem/early progenitor cells and trichofolliculoma-like skin hyperplasia. "