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Anonychia congenita

The absence of fingernails and toenails (anonychia) and its milder phenotypic variant (hyponychia), are usually associated with other skeletal and limb abnormalities in genetic syndromes. Isolated nonsyndromic cases are less common and may show autosomal recessive inheritance and variable expression within a given family. The nail phenotypes can vary from no nail field to a nail field of reduced size with an absent or rudimentary nail. Nonsyndromic cases are associated with mutations in the R-spondin 4 (RSPO4) gene. OMIM: 610573
Also Known As:
Anonychia; Hyponychia congenita
Networked: 10 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Coinfection
2. Skin Diseases (Skin Disease)
3. Pain (Aches)
4. Necrosis
5. Congenital Abnormalities (Deformity)

Experts

1. Cameron, A: 1 article (12/2013)
2. Craig, P: 1 article (12/2013)
3. Hunt, W T: 1 article (12/2013)
4. de Berker, D A: 1 article (12/2013)
5. Ahmad, Wasim: 1 article (01/2013)
6. Wasif, Naveed: 1 article (01/2013)
7. Agarwal, Nagamani: 1 article (12/2012)
8. Babu, Suresh: 1 article (12/2012)
9. Miller, Hollman: 1 article (04/2010)
10. Rodríguez, Gerzaín: 1 article (04/2010)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Anonychia congenita:
1. Proteins (Proteins, Gene)FDA Link
2. LigandsIBA
3. FurinIBA
4. Nonsense Codon (Nonsense Mutation)IBA
5. Phenytoin (Dilantin)FDA LinkGeneric
6. Cysteine (L-Cysteine)FDA Link
7. Adrenal Cortex Hormones (Corticosteroids)IBA
8. prothipendylIBA

Therapies and Procedures

1. Therapeutics
2. Surgical Amputation (Amputations)