Idiopathic dilation cardiomyopathy

Dilated cardiomyopathy that is characterized by cardiac dilatation and reduced systolic function. It is the most frequent form of cardiomyopathy and accounts for more than half of all cardiac transplantations performed in children between 1 and 10 years of age. For CMD1A, 20 to 30% of cases are heritable and show an autosomal dominant inheritance pattern. Germline mutations in the LMNA gene have been identified. OMIM: 115200

Also Known As:

Cardiomyopathy, Dilated, 1h; Cardiomyopathy, Dilated, With Conduction Defect; Dilated cardiomyopathy with conduction defect

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy)
2.	Emery-Dreifuss Muscular Dystrophy (Scapuloperoneal Muscular Dystrophy)
3.	Progeria (Hutchinson Gilford Syndrome)
4.	Lipodystrophy
5.	Laminopathies

Experts

1.	Dubbioso, Raffaele: 1 article (04/2015)
2.	Fiorillo, Chiara: 1 article (04/2015)
3.	Iodice, Rosa: 1 article (04/2015)
4.	Manganelli, Fiore: 1 article (04/2015)
5.	Ruggiero, Lucia: 1 article (04/2015)
6.	Santorelli, Filippo: 1 article (04/2015)
7.	Santoro, Lucio: 1 article (04/2015)
8.	Soscia, Ernesto: 1 article (04/2015)
9.	Storti, Eugenia: 1 article (04/2015)
10.	Tessa, Alessandra: 1 article (04/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Idiopathic dilation cardiomyopathy:

1.	Lamin Type A (Lamin A)IBA 04/01/2015 - "Mutations in the lamin A/C protein cause laminopathies, a heterogeneous group of disorders that include recessive axonal neuropathy (CMT2B1), Emery-Dreifuss muscular dystrophy (EDMD), limb-girdle muscular dystrophy (LGMD), dilated cardiomyopathy with conduction defect, and different forms of lipodystrophy and progeria. "
2.	LaminsIBA 04/01/2003 - "Mutations in A-type lamins also cause limb-girdle muscular dystrophy type 1B, dilated cardiomyopathy with conduction defect, and Charcot-Marie-Tooth disorder type 2B1. "
3.	Proteins (Proteins, Gene)FDA Link 04/01/2015 - "Mutations in the lamin A/C protein cause laminopathies, a heterogeneous group of disorders that include recessive axonal neuropathy (CMT2B1), Emery-Dreifuss muscular dystrophy (EDMD), limb-girdle muscular dystrophy (LGMD), dilated cardiomyopathy with conduction defect, and different forms of lipodystrophy and progeria. "