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Complete atrioventricular septal defect

A large hole in center of the heart, where all four chambers would normally be divided.
Also Known As:
Common atrioventricular canal; Complete atrioventricular canal
Networked: 87 relevant articles (3 outcomes, 3 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Pulmonary Hypertension
2. Pulmonary Embolism
3. Down Syndrome (Down's Syndrome)
4. Patent Ductus Arteriosus
5. Pulmonary Atresia With Ventricular Septal Defect

Experts

1. Jacobs, Jeffrey P: 7 articles (01/2021 - 04/2010)
2. Bacha, Emile A: 5 articles (01/2021 - 01/2007)
3. Pizarro, Christian: 5 articles (01/2021 - 12/2011)
4. Hill, Kevin D: 5 articles (01/2019 - 03/2016)
5. Mayer, John E: 5 articles (01/2019 - 01/2007)
6. Overman, David M: 5 articles (01/2019 - 03/2016)
7. Pasquali, Sara K: 5 articles (01/2019 - 12/2011)
8. Backer, Carl L: 4 articles (01/2019 - 03/2016)
9. Jacobs, Marshall L: 4 articles (01/2019 - 03/2016)
10. St Louis, James D: 4 articles (01/2019 - 03/2016)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Complete atrioventricular septal defect:
1. Bosentan (Tracleer)FDA Link
2. A 17 (A-17)IBA
3. Coenzyme A (CoA)IBA
4. Oxygen (Dioxygen)IBA
5. Dihydrotachysterol (AT 10)IBA
6. Anesthetics (Anesthetic Agents)IBA
7. N 30IBA
8. A 7 (A-7)IBA
9. AngiopoietinsIBA
10. DexmedetomidineFDA Link

Therapies and Procedures

1. Lung Transplantation
2. Extracorporeal Membrane Oxygenation
3. Sternotomy
4. Arterial Switch Operation
5. Norwood Procedures
01/01/2019 - "Surgeons may submit Norwood procedures, complete atrioventricular canal repairs, and/or arterial switch operations. "
01/01/2020 - "The study cohort consisted of infants aged ≤12 months undergoing definitive surgery for complete atrioventricular septal defect, tetralogy of Fallot, dextro-transposition of the great arteries with or without intact ventricular septum, single ventricle (Norwood procedure), and coarctation or interrupted/hypoplastic arch with ventricular septal defect. "
01/01/2021 - "In a prospective, multicenter, observational study, 17 sites enrolled 1,149 infants undergoing 5 common operations: tetralogy of Fallot repair (n = 250), complete atrioventricular septal defect repair (n = 249), arterial switch operation (n = 251), coarctation or interrupted arch with ventricular septal defect (VSD) repair (n = 150), and Norwood operation (n = 249). "
01/01/2018 - "This analysis documents the overall aggregate Operative Mortality (interquartile range among all participating programs) for the following procedural groups: off-bypass coarctation repair, 1.3% (0.0% to 1.4%%); ventricular septal defect repair, 0.6% (0.0% to 0.9%); tetralogy of Fallot repair, 1.1% (0.0% to 2.0%); complete atrioventricular canal repair, 2.7% (0.0% to 4.4%); arterial switch operation, 2.2% (0.0% to 2.9%); arterial switch operation and ventricular septal defect repair, 5.1% (0.0% to 8.3%); Glenn/HemiFontan, 2.1% (0.0% to 3.1%); Fontan operation, 1.1% (0.0% to 0.0%); truncus arteriosus repair, 10.1% (0.0% to 15.4%); and Norwood procedure, 15.8% (9.0% to 25.0%)."
03/01/2017 - "This analysis documents the overall aggregate operative mortality (interquartile range among all participating programs) for the following procedural groups: off-bypass coarctation repair, 1.3% (0.0% to 1.8%); ventricular septal defect repair, 0.6% (0.0% to 0.9%); tetralogy of Fallot repair, 1.1% (0.0% to 1.4%); complete atrioventricular canal repair, 3.0% (0.0% to 4.7%); arterial switch operation, 2.7% (0.0% to 4.1%); arterial switch operation and ventricular septal defect repair, 5.3% (0.0% to 6.7%); Glenn/hemi-Fontan, 2.5% (0.0% to 4.5%); Fontan operation, 1.2% (0.0% to 1.2%); truncus arteriosus repair, 9.4% (0.0% to 16.7%); and Norwood procedure, 15.7% (8.9% to 25.0%)."