Hecht syndrome

Mouth, inability to open completely, and short finger-flexor tendons

Also Known As:

Arthrogryposis, Distal, Type 7; Trismus-Pseudocamptodactyly Syndrome; Trismus-pseudocamptodactyly

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
2.	Arthrogryposis
3.	Freeman-Sheldon syndrome

Drugs and Important Biological Agents (IBA) related to Hecht syndrome:

1.	Cardiac MyosinsIBA 07/02/2023 - "Mutations at a highly conserved homologous residue in three closely related muscle myosins cause three distinct diseases involving muscle defects: R671C in β-cardiac myosin causes hypertrophic cardiomyopathy, R672C and R672H in embryonic skeletal myosin cause Freeman Sheldon syndrome, and R674Q in perinatal skeletal myosin causes trismus-pseudocamptodactyly syndrome. "
2.	Myosin Heavy Chains (Myosin Heavy Chain)IBA 02/01/2013 - "The second phenotype, observed in four unrelated families, is autosomal dominant trismus-pseudocamptodactyly syndrome (distal arthrogryposis type 7; previously associated exclusively with myosin heavy chain 8 mutations). "
3.	Myosins (Myosin)IBA 07/02/2023 - "Mutations at a highly conserved homologous residue in three closely related muscle myosins cause three distinct diseases involving muscle defects: R671C in β-cardiac myosin causes hypertrophic cardiomyopathy, R672C and R672H in embryonic skeletal myosin cause Freeman Sheldon syndrome, and R674Q in perinatal skeletal myosin causes trismus-pseudocamptodactyly syndrome. "