Pseudoangiomatous stromal hyperplasia

A benign proliferation of the STROMAL CELLS in the breast.

Also Known As:

Mammary pseudoangiomatous stromal hyperplasia; Pseudoangiomatous stromal hyperplasia of the breast

Networked: 19 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Cardiovascular Diseases: 91362
- Vascular Diseases: 15138
  - Angiomatosis: 248
    - Pseudoangiomatous stromal hyperplasia: 19
Skin and Connective Tissue Diseases
- Skin Diseases: 13127
  - Breast Diseases: 1550
    - Pseudoangiomatous stromal hyperplasia: 19
Signs and Symptoms Pathological Conditions
- Pathologic Processes: 10023
  - Hyperplasia: 27760
    - Pseudoangiomatous stromal hyperplasia: 19

Related Diseases

1.	Adenomyoepithelioma
2.	Fibroadenoma
3.	Aggressive Fibromatosis (Desmoid)
4.	Osteosarcoma (Osteogenic Sarcoma)
5.	Muscle Tissue Neoplasms

Experts

1.	Aguila-Seara, Gabriela: 1 article (08/2022)
2.	Cairns, Ashley: 1 article (08/2022)
3.	Chiba, Akiko: 1 article (08/2022)
4.	Ghandili, Mehrnoosh: 1 article (08/2022)
5.	Howard-McNatt, Marissa: 1 article (08/2022)
6.	Jones, V Morgan: 1 article (08/2022)
7.	LeRoy Coldren, Daniel: 1 article (08/2022)
8.	Marks, Malcolm W: 1 article (08/2022)
9.	Miller-Ocuin, Jennifer: 1 article (08/2022)
10.	Steele, Thomas: 1 article (08/2022)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Pseudoangiomatous stromal hyperplasia:

1.	von Willebrand FactorIBA 01/01/2005 - "Immunohistochemical staining showed that endothelial cells lining true blood vessels were positive for Factor VIII-related antigen, but the spindle cells were negative for Factor VIII. Pseudoangiomatous stromal hyperplasia was diagnosed."
2.	Tamoxifen FDA LinkGeneric 11/01/2001 - "Tamoxifen in the management of pseudoangiomatous stromal hyperplasia."
3.	Melanocyte-Stimulating Hormones (MSH)IBA 10/01/2021 - "MSH has overlapping features with the fascicular pattern of PASH and is likely related to pseudoangiomatous stromal hyperplasia (PASH) but differs in that does not demonstrate pseudovascular structures and it predominantly involves perilobular stroma. "
4.	Hormones (Hormone)IBA 12/01/2020 - "The effect of hormones on an uncommon breast disorder pseudoangiomatous stromal hyperplasia: a case report and literature review."
5.	Factor VIII (Coagulation Factor VIII)IBA 01/01/2005 - "Immunohistochemical staining showed that endothelial cells lining true blood vessels were positive for Factor VIII-related antigen, but the spindle cells were negative for Factor VIII. Pseudoangiomatous stromal hyperplasia was diagnosed."
6.	Estrogens (Estrogen)FDA Link 01/01/2020 - "Unilateral pseudoangiomatous stromal hyperplasia in a transgender (male to female) woman on estrogen therapy."
7.	Contraceptive Agents (Contraceptives)IBA 01/01/2020 - "An unusual cause of breast hypertrophy: pseudoangiomatous stromal hyperplasia secondary to contraceptive implant."
8.	CollagenIBA 01/01/2018 - "Pseudoangiomatous stromal hyperplasia (PASH) is a benign breast condition of collagen proliferation. "
9.	methylamphotericin B (AME)IBA 01/01/2015 - "Following histopathological, immunohistochemical, and clinical evaluations, the patients were diagnosed as follows: pseudoangiomatous stromal hyperplasia (PASH), bilateral desmoid-type fibromatosis (FM), adenomyoepithelioma (AME), myofibroblastoma (MFB), malignant phyllodes tumor (MF), high-grade AS, post-chemotherapy osteosarcoma (OS) + Paget's disease, and metaplastic carcinoma (MC). "
10.	gallium 68 PSMA-11IBA 01/01/2017 - "68Ga-PSMA Expression in Pseudoangiomatous Stromal Hyperplasia of the Breast."

Therapies and Procedures

1.	Mastectomy (Mammectomy) 08/01/2022 - "Bilateral Diffuse Pseudoangiomatous Stromal Hyperplasia Necessitating Mastectomy." 12/01/2018 - "Bilateral diffuse tumorous pseudoangiomatous stromal hyperplasia treated with bilateral mastectomy in a 40-year-old woman." 04/01/2018 - "Concurrent giant tumoral pseudoangiomatous stromal hyperplasia necessitating bilateral mastectomy." 01/01/2014 - "Bilateral diffuse tumorous pseudoangiomatous stromal hyperplasia: a case of bilateral mastectomy in a 29-year-old woman." 04/01/2011 - "Pseudoangiomatous stromal hyperplasia of the breast: an unusual pathology necessitating bilateral mastectomy during pregnancy."
2.	Mammaplasty (Breast Reconstruction) 01/01/2023 - "This case report describes a 16-year-old girl with a severe case of bilateral pseudoangiomatous stromal hyperplasia that was managed with reduction mammoplasty, along with a 10-year case follow-up. " 01/01/2020 - "Successful management of diffuse bilateral pseudoangiomatous stromal hyperplasia of the mammary glands by reductive mammoplasty."
3.	Subcutaneous Mastectomy 02/01/2023 - "Repeated recurrence of bilateral gigantomastia after subcutaneous mastectomy caused by tumoral pseudoangiomatous stromal hyperplasia: a case report and review of literature."
4.	Segmental Mastectomy (Lumpectomy) 01/01/2018 - "The histological examination of the lumpectomy specimen showed fibroadenoma with peculiar stromal alteration consistent with pseudoangiomatous stromal hyperplasia. "
5.	Therapeutics 01/01/2020 - "Unilateral pseudoangiomatous stromal hyperplasia in a transgender (male to female) woman on estrogen therapy."