Pruritic urticarial papules plaques of pregnancy

A condition characterized by pruritic urticarial papules and plaques or polymorphic eruptions during the later stages of pregnancy. It usually appears first in abdominal striae before spreading to other areas. The eruption clears soon after delivery and may be hereditary with autosomal dominant inheritance. OMIM: 178995

Also Known As:

PUPPP Pruritic urticarial papules plaques of pregnancy; Polymorphic eruption of pregnancy; Pruritic Urticarial Papules And Plaques of Pregnancy; Pruritic urticarial papules and plaques of pregnancy, familial

Networked: 18 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Pemphigoid Gestationis (Herpes Gestationis)
2.	Epidural Abscess
3.	Pruritus (Itching)
4.	Prurigo
5.	Inflammation (Inflammations)

Experts

1.	Dokuzeylul Gungor, Nur: 1 article (03/2021)
2.	Gurbuz, Tugba: 1 article (03/2021)
3.	Ture, Tugba: 1 article (03/2021)
4.	Habe, Koji: 1 article (01/2021)
5.	Ishikawa-Nishimura, Mai: 1 article (01/2021)
6.	Kondo, Makoto: 1 article (01/2021)
7.	Matsushima, Yoshiaki: 1 article (01/2021)
8.	Yamanaka, Keiichi: 1 article (01/2021)
9.	Kim, En Hyung: 1 article (01/2017)
10.	Hann, S K: 1 article (04/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Pruritic urticarial papules plaques of pregnancy:

1.	CytokinesIBA 01/01/2021 - "A Case of Pruritic Urticarial Papules and Plaques of Pregnancy: Pathophysiology and Serum Cytokine Profile." 07/01/2006 - "Relevance of cellular infiltrate and cytokines in polymorphic eruption of pregnancy (PEP)."
2.	Proteins (Proteins, Gene)FDA Link 05/01/1999 - "Polymorphic eruption of pregnancy and herpes gestationis: comparison of granulated cell proteins in tissue and serum."
3.	Progesterone FDA LinkGeneric 12/01/2007 - "This latter group encompass pruritus gravidarum with or without intrahepatic cholestasis, pemphigoid gestationis, polymorphic eruption of pregnancy, prurigo gestationis, acute folliculitis of pregnancy, impetigo herpetiformis and the progesterone auto-immune dermatitis. "
4.	ParaffinIBA 12/01/2013 - "The utility of C4d immunohistochemistry on formalin-fixed paraffin-embedded tissue in the distinction of polymorphic eruption of pregnancy from pemphigoid gestationis."
5.	MucinsIBA 05/01/1988 - "We have recently demonstrated that in pruritic urticarial papules and plaques of pregnancy (PUPPP) there are multiple dermal fibroblasts with no deposition of mucin. "
6.	ImmunosorbentsIBA 06/01/2005 - "Usefulness of BP180 NC16a enzyme-linked immunosorbent assay in the serodiagnosis of pemphigoid gestationis and in differentiating between pemphigoid gestationis and pruritic urticarial papules and plaques of pregnancy."
7.	Hormones (Hormone)IBA 03/01/2021 - "Pruritic urticarial papules and plaques of pregnancy development may have a strong relationship with hormone treatments during in vitro fertilization and hormonal changes during pregnancy. "
8.	Formaldehyde (Formol)FDA Link 12/01/2013 - "The utility of C4d immunohistochemistry on formalin-fixed paraffin-embedded tissue in the distinction of polymorphic eruption of pregnancy from pemphigoid gestationis."
9.	Estrogens (Estrogen)FDA Link 04/01/2001 - "The purpuric lesions may be secondary to high capillary permeability, increased by severe dermic inflammation of the polymorphic eruption of pregnancy and, possibly, high level of circulating estrogens."
10.	EnzymesIBA 06/01/2005 - "Usefulness of BP180 NC16a enzyme-linked immunosorbent assay in the serodiagnosis of pemphigoid gestationis and in differentiating between pemphigoid gestationis and pruritic urticarial papules and plaques of pregnancy."

Therapies and Procedures

1.	Intramuscular Injections 01/01/2017 - "Pruritic Urticarial Papules and Plaques of Pregnancy Occurring Postpartum Treated with Intramuscular Injection of Autologous Whole Blood." 04/01/2015 - "Three cases of pruritic urticarial papules and plaques of pregnancy (PUPPP) treated with intramuscular injection of autologous whole blood."
2.	Epidural Analgesia 10/01/2006 - "To describe the risk factors for epidural abscess (EA) formation following epidural analgesia in a parturient with pruritic urticarial papules and plaques of pregnancy (PUPPP). "
3.	Fetal Version (External Cephalic Version) 09/01/2004 - "A case of pruritic urticarial papules and plaques of pregnancy associated with external cephalic version."
4.	Induced Labor 05/01/2006 - "Pruritic urticarial papules and plaques of pregnancy is a condition significantly associated with multiple pregnancies, hypertensive disorders, and induction of labor. "