HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

satropane

structure in first source

Also Known As:

S(-)-satropane; lesatropane

Networked: 5 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Aza Compounds: 3
  - Azabicyclo Compounds
    - Tropanes: 1
      - satropane: 5
Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Tropanes: 1
    - satropane: 5
- Bridged-Ring Heterocyclic Compounds
  - Tropanes: 1
    - satropane: 5
  - Heterocyclic Bridged Bicyclo Compounds
    - Azabicyclo Compounds
      - Tropanes: 1
        satropane: 5

Experts

1.	Chen, Hong-Zhuan: 4 articles (01/2017 - 11/2008)
2.	Lu, Yang: 4 articles (08/2013 - 02/2008)
3.	Yang, Li-Min: 2 articles (08/2013 - 09/2011)
4.	Cui, Yong-Yao: 1 article (01/2017)
5.	Hou, Li-Na: 1 article (01/2017)
6.	Liu, Lu: 1 article (01/2017)
7.	Lu, Juan-Juan: 1 article (01/2017)
8.	Song, Yun: 1 article (01/2017)
9.	Tang, Ya-Bin: 1 article (01/2017)
10.	Yu, Ping: 1 article (01/2017)

Related Diseases

1.	Ischemia 01/01/2017 - "In our study, we evaluated the potential neuroprotective effect of L-satropane, a novel mAChR agonist, on retinal neuronal injury induced by cobalt chloride (CoCl2) and ischemia/reperfusion (I/R). "
2.	Hypotension (Low Blood Pressure) 02/01/2008 - "The assays for radioligand-receptor binding, the contractile responses of isolated iris muscle, the miosis response, and the intraocular hypotension of the enantiomers of satropane were investigated. " 02/01/2008 - "To study the stereoselectivity of satropane (3-paramethylbenzene sulfonyloxy-6-acetoxy tropane), a novel tropane analog, on iris muscarinic receptor activation and intraocular hypotension. " 02/01/2008 - "Stereoselectivity of satropane, a novel tropane analog, on iris muscarinic receptor activation and intraocular hypotension."
3.	Glaucoma 11/04/2008 - "S(-)-Satropane is currently being developed to in situ forming ophthalmic gel, a new ophthalmic delivery system, for the treatment of glaucoma. " 09/01/2011 - "Lesatropane is a novel muscarinic receptor agonist and is currently being under preclinical development in China as a single enantiomer drug for the treatment of primary glaucoma. " 08/01/2013 - "Lesatropane, a synthesized chiral tropane (3S, 6S-isomer of satropane), is a novel muscarinic agonist, and is being under preclinical development in China for the treatment of primary glaucoma. "
4.	Miosis 02/01/2008 - "The assays for radioligand-receptor binding, the contractile responses of isolated iris muscle, the miosis response, and the intraocular hypotension of the enantiomers of satropane were investigated. " 02/01/2008 - "In the pupil diameter measurement assay in vivo, S(-)satropane induced miosis much more effectively than pilocarpine, while R(+)satropane failed to produce any miosis. "
5.	Hypoxia (Hypoxemia) 01/01/2017 - "CoCl2-induced hypoxia injury in cultured cell models and I/R-induced retinal neuronal damage in rats in vivo were used to evaluate the abilities of L-satropane. "

Related Drugs and Biologics

1.	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)
2.	Neuroprotective Agents
3.	Retinaldehyde (Retinal)
4.	cobaltous chloride (cobalt(II)chloride)
5.	satropane
6.	Muscarinic Agonists
7.	Pilocarpine (Ocusert)